Hepatic Regeneration
Macrophage inflammatory protein 2 aids regeneration after hepatectomy
Published in Blood Weekly, September 18th, 2003
"Recent studies show CXC chemokine elevations after hepatic resection; blockade of epithelial neutrophilactivating protein (ENA-78), a CXC chemokine, retards hepatic regeneration after resection. Additional studies demonstrate that exogenous macrophage inflammatory protein (MIP)-2, another CXC chemokine, is therapeutic in a murine acetaminophen toxicity model when other therapies fail," scientists in the United States report.
"The current investigations study MIP-2's effects on the cellular mechanisms involved in liver regeneration in mice after 70% hepatectomy,"...
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Source: Blood Weekly (2003-09-18)
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