Transplant Research
GM-CSF restores innate immunity cytokines in immunosuppressed human blood
Published in Blood Weekly, September 18th, 2003
"Infection remains the major complication of immunosuppressive therapy in organ transplantation. Therefore, reconstitution of the innate immunity against infections, without activation of the adaptive immune responses, in order to prevent graft rejection is a clinically desirable status in transplant recipients. We found that GM-CSF restored TNF mRNA and protein expression without inducing IL-2 production and T cell proliferation in glucocorticoid-immunosuppressed blood from either healthy donors or liver transplant patients," scientists in Germany...
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Source: Blood Weekly (2003-09-18)
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