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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . September 25th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Blood Substitute - Novel oxygen carrier does not disrupt blood cell morphology in vitro

Stem-Cell Transplantation - Umbilical cord blood transplants may be effective against neurological disorders

Atherosclerosis - Platelet-activating factor associates with the angiogenesis of arterial lesions

Bleeding Disorders - Acquired factor VIII deficiency can be treated with activated factor VII

Leukemia Therapy - Hydroxyurea improves interferon therapy for leukemia

Stem-Cell Transplantation - Immature leukocyte monitoring may aid PBSC harvest

AIDS Prevention - Human rights group: China's denial of AIDS problem propels HIV/AIDS

B-Lymphocyte Development - Interferon regulatory factors IRF-4,8 are involved in pre-BCR to B switch

Benign Lymph Tumor - Sphenoid sinus lymphangioma is an extremely rare benign lymph tumor

Blood Donation - FDA clears blood bank donor solution

Blood Testing - The Blood Center implements Surround System 3.1

Bone Repair - FDA approval granted to initiate trial for bone graft product

Cancer Research - Gene needed for antibody-producing cell development is key to blood cell cancer

Cancer Therapy - Multimodal treatment of adrenocortical cancer effective

Cloning Research - Grant renews funding of research toward cloning primates

Compromised Immune System - FDA approval granted for Gamunex

Corporate Update - Stem cell banking firm reports on annual shareholders' meeting

DNA Testing - Two-phase research collaboration designed to improve diagnostic testing

Diagnostics - Anion-exchange HPLC can be used to measure serum lipoprotein cholesterols

Dialysis Catheters - Researchers review various chronic peritoneal dialysis catheters

Expansion - Company expands coating clean room facility to accommodate demand

Gastroenterology - Lumbar spine BMD measurements don't predict post liver transplant fracture risk

Genetic Disorders - Hirschsprung disease linked to neural crest stem-cell defects

HLA Alleles - Two new HLA-B variants are found

Hairy Cell Leukemia - Rituximab has only modest single-agent activity against HCL in a Phase 2 study

Heart Transplants - Study: Everolimus significantly reduces the risk of complications

Hematologic Malignancy - p16(INK4A) and p14(ARF) is often overexpressed in hematological malignancies

Hematology - Bone marrow stem cells conduct the vasculogenesis of solid tumor growth

Hematology - Hepatitis C virus upregulates interferon type I receptors in blood cells

Hematology - RNA trans-splicing corrects genetic defects in hemophilia A models

Hematopoietic Stem Cells - Osiris Therapeutics awards mesenchymal stem-cell technology rights in Japan

Hemophilia - Inhibitors in hemophilia A tend to be managed by immune tolerance approaches

Hepatitis B Virus - Additional data submitted for Nabi-HB Intravenous BLA

Immune Enhancers/Stabilizers - Myelopeptides are immunostabilizers, antibody inducers, anticancer effectors

Immunology - Macrophages control B-cell retention and trafficking in the splenic marginal zone

Immunology - Researchers link stem cells to T cells

Leptospirosis Virulence - A new virulence factor is associated with highly pathogenic Leptospira

Leukemia - Functional markers could be helpful to predict clinical behavior of ALL

Leukemia - Hospitals identify ways to improve treatment of childhood leukemia in Honduras

Leukemia - Several ETS genes may play key roles in hematopoietic differentiation

Leukemia - Survival of acute myeloid leukemia cells requires PI3 kinase activation

Leukemia Genetics - A new HMGA2 locus rearrangement is found in acute lymphoblastic leukemia

Liver Failure - HCV genotype 4 patients suffer worse liver disease after liver transplantation

Lung Cancer - Early treatment with epoetin alfa maintains hemoglobin levels during chemotherapy

Lyme Disease Erythema - Erythema migrans can be tested for Borrelia using BBK32 antigens

Lymphoma - Complement activation determines the therapeutic activity of rituximab in vivo

Lymphoma - Monoclonal antibodies are showing promise in Phase I and II trials for lymphoma

Lymphoma - Non-Hodgkin lymphoma can present with acute liver failure

Lymphoproliferation - Darbepoetin alfa benefits anemic patients with lymphoproliferative cancers

Malaria Diagnosis - With proper purification, length of storage does not affect diagnostic utility of dried blood spots

Myeloid Malignancy - Farnesyl transferase inhibitors may play role in myeloid malignancy treatment

Myeloma - Patient with IgD multiple myeloma, on hemodialysis, improved with thalidomide

Neonatal Medicine - Fetal hemoglobin composition does not affect hyperbilirubinemia risk

Neuroimmune Effectors - Neurotrophins are involved in nervous and immune system, thymus development

Osteomyelitis -  Bartonella henselae genotype I is capable of causing osteomyelitis

Otology - Chicken embryo research tunes into inner ear

Pediatric Immunology - Neonatal Th-1 cytokine deficiencies may underlie infection susceptibility

Peritoneal Dialysis - Three purse-string sutures result in a low incidence of leakage

Renal Tumors - Cryoablation may be an option for patients with tumor in a solitary kidney

SARS - Positive results reported with Neugene antisense compound

Stem-Cell Research - Flt3+ stem-cell populations contain early dendritic cell precursors

Stem-Cell Research - Functional interaction seen between CD34(+) and CD34(-) Lin(-) stem cells

Stem-Cell Research - Mesenchymal stem cells differentiate into cardiovascular cells after injection into heart

Stem-Cell Research - Novel culture system enables cultivation of neural stem cells from adult rat subependyma

Stem-Cell Research - X-linked female embryonic stem-cell genes carry epigenetic mark prior to X inactivation

Stem-Cell Transplantation - Haploidentical PBSCT based on fetomaternal tolerance feasible

Stem-Cell Transplantation - Mechanisms of defibrotide activity clarified

Stem-Cell Transplantation - Stem cell grafts may enhance lung regeneration

Transfusion - Hepatitis G virus prevalence among cancer patients in Turkey is low

Transplant Medicine - Retrovirus-based selection makes cells more resistant to cytotoxin

Transplantation - Hepatitis B core antibody positivity doesn't rule out liver lobe donation

West Nile Virus - Collaborative effort to develop West Nile hyperimmune globulin

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