Atherosclerosis
Platelet-activating factor associates with the angiogenesis of arterial lesions
Published in Blood Weekly, September 25th, 2003
According to a study from Italy, "platelet-activating factor (PAF) is a phospholipid mediator synthesized by activated inflammatory and endothelial cells. Recently PAF has been shown to contribute to neoangiogenesis in several experimental models. Here we evaluated the presence of PAF and its potential role in neovascularization within human atherosclerotic plaques."
"The amount of PAF extracted from 18 carotid plaques (266.65±40.07 pg/100 mg dry tissue; mean ± SE) was significantly higher than that extracted from 18 normal arterial specimens (6 from...
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Source: Blood Weekly (2003-09-25)
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