Susan Hasty, Publisher
Table of Contents . . . October 2nd, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Stem-Cell Transplantation - Intensive SCT conditioning regimen effective for high-risk leukemia patients
Stem-Cell Transplantation - Oral tolerance induction may reduce GVHD risk in stem-cell graft recipients
Blood Substitute - Novel LC-based assay detects Hemopure doping in athletes
Chronic Myeloid Leukemia - Stem cell transplantation benefits confirmed for pediatric CML patients
Stem-Cell Transplantation - Fludarabine-melphalan regimen increases post-SCT T-cell engraftment, GVHD risk
Stem-Cell Transplantation - Monthly chimerism analysis can predict stem-cell graft failure
Aging - CD8 T, CD16 NK have different telomere shortening rates, telomerase activity
Anemia - Hepcidin is critical for iron transport, macrophage iron collection
B Cell Differentiation - Transcription coactivator OCA-B gene may be involved in B-cell expansion
Bacteremia - Alpha-proteobacterium in an immunocompetent geriatric patient causes bacteremia
Blood Transfusion - Trials for investigational pathogen inactivation system halted
Cancer Histology - Primary central nervous system lymphoma can have cryoglobulin deposits
Cancer Therapy - Dosing regimens polarize the mobility and viability of vessel progenitor cells
Cardiac Testing - 10-Minute cardiac troponin I test receives U.S. FDA clearance
Cell Therapy - Novel source found in human embryonic stem-cell-derived cardiomyocytes
Cesarean Section - C-section has minor risk of maternal HSV-2 brain inflammation
Chronic Hepatitis C - Several hematologic disorders are linked to hepatitis C virus infection
Congestive Heart Failure - Stem cell therapy is a safe tool for mending broken hearts
Coronary Stenting - New data confirms safety of Lipitor in combination with anti-blood-clotting drug
Critical Care Medicine - C1 inhibitor benefits sepsis due to lowering of neutrophil activation
Deep Vein Thrombosis - FDA clears VIDAS D-Dimer New
Dengue Virus - NS1 serotype specific IgG ELISA distinguishes primary, secondary infection
Diagnostics - Toxoplasma gondii ELISA can give false-positive IgM due to sphingolipids
Funding - Grant awarded to develop hepatitis C virus drug susceptibility assay
Gene Therapy - Lengthened targeting arms do not increase HR efficiency in stem-cell beta-globin locus
Genomics - Expression of the novel gene asrij overlaps with vascular markers
Graft-versus-Host Disease - Programmed death-1 is involved in protection from GVHD lethality
HIV Progression - Disease development can be monitored and predicted
Heart Disease Diagnosis - Stem-cell company provides cardiac risk assessment calculator
Heart Failure - Researchers describe stem-cell therapy for myocardial repair, regeneration
Hematology - Cytotoxic T lymphocytes can be generated ex vivo to target multiple myeloma
Hematology - Negative selection augments the characterization of bone marrow derivatives
Hysterectomy - Platelet populations become different after abdominal uterine removal
Immunogenetic Database - 89 Killer immunoglobin-like receptor alleles (KIR) have been sequenced
Immunotherapy - Divergent virology can affect the outcome of ex vivo T-cell expansion
Leukemia - Arsenic trioxide is effective against acute promyelocytic leukemia
Leukemia - Flavonoids can differentially modulate the efficacy of chemotherapeutics
Leukemia - Researchers validate the Hammersmith prognostic scoring system
Leukemia - Vigorous studies required for understanding, management of NK leukemia, lymphoma
Leukemia Therapy - Allogeneic SCT superior to autotransplantation for young leukemia patients
Leukemia Therapy - Chromosome 9 inversion linked to poor stem-cell transplantation outcome
Lymphoma - Cutaneous T- and B-cell lymphoma need subclassification, specific treatment
Lymphoma - Global patient organization launched to help millions with lymphoma
Melanoma - Positive, long-term, follow-up data reported from phase I trial of GVAX
Mergers and Acquisitions - Company discusses GenSci merger and announces plans to streamline
Mutiple Myeloma - Multiple myeloma patients may appear to have hyperphosphatemia due to artifact
Mycotoxins - Ochratoxin A and some metabolites alter kidney cell surface marker expression
Myelodysplastic Syndrome - Myelodysplastic syndrome may occur after acute promyelocytic leukemia
Myelodysplastic Syndrome - Philadelphia chromosome may be involved in bone marrow suppression
Myeloma - Plasmablastic transformation and acute leukemia can result from multiple myeloma
Neuroscience - Cerebral microvessel reactions vary in response to focal ischemia
Non-Hodgkin Lymphoma - Combined rituximab and G-CSF treatment yields long remission times
Nosocomial Infection - Listeria moncytogenes cross-contaminates infants in a newborn nursery
Obstetrics - Several factors combine in late pregnancy to increase hemolytic uremic syndrome
Personnel - Mitchell Seyedin, PhD, named president and CEO of tissue-repair company
Personnel - PolyHeme maker names Eva C. Essig VP regulatory affairs
Proteolysis - Monocytes starved of glutamine during infection can't degrade all proteins
Proteomics - Structure dictates Hsp90 role in heme activator protein Hap1 activation
Renal Failure - Slovenian hemodialysis patients experience low viral hepatitis rates
Rickettsia - LepB gene for signal peptidase is similar in R. rickettsii, R. typhi
SARS - Alliance with NIH, USARMID targets discovery of therapeutics against SARS
Sickle Cell Anemia - Patient enrollment completed for phase II ICA-17043 trial
Sickle Cell Disease - Hemoxin issued orphan drug status by U.S. FDA
Stem-Cell Research - A novel technique enhances embryonic and neuronal stem-cell labeling
Stem-Cell Research - CD184 and alpha4beta1 integrins mediate CD34+ cell pseudoemperipolesis
Stem-Cell Research - Hematopoietic cell Hmgb3 expression prevents myeloid and B-cell differentiation
Stem-Cell Research - Inhibition of p21 expression can aid hematopoietic cell expansion
Stem-Cell Research - Mobilized HSCs later return to marrow
Stem-Cell Research - Novel EGFP reporter mouse line useful for hematopoietic cell study
Stem-Cell Research - Somatic nucleus reprogramming may be feasible
Stem-Cell Transplantation - Antithymocyte globulin improves outcome for unrelated stem-cell transplantation
Stem-Cell Transplantation - Beta-blockers may ameliorate GAVE in SCT recipients
Stem-Cell Transplantation - N-acetyl-L-cysteine does not affect busulfan pharmacokinetics
Stem-Cell Transplantation - Serial cytokine monitoring can help identify GVHD patients
Stem-Cell Transplantation - Serum stem-cell growth factor levels useful for monitoring post-SCT recovery
Stock Listing - Safety syringe company to apply for OTC Bulletin Board
Streptococcal Infections - Toxic shock syndrome may be treatable with IVIG therapy
Stroke - Immunoliposomes can reduce hemorrhage risk after tPA treatment for stroke
Systemic Lupus Erythematosus - Anti-SOD autoantibodies may allow damage by radicals in SLE
Thymocyte Differentiation - TCR signal strength controls GATA-3 levels, regulating T-cell differentiation
Toxic Shock Syndrome - TSS toxin-1 has a novel domain of the SAG molecule that binds MHC-II
Transplant Medicine - M-T7 protein from myxoma virus may attenuate transplanted kidney rejection
Transplant Medicine - Pregnancy outcome is good following functionally stable kidney transplants
West Nile Virus - Deal signed to share development of West Nile virus hyperimmune globulin
West Nile Virus - NIAID opens innovative treatment study
West Nile Virus - New test quickly diagnoses virus infection
Wiskott-Aldrich Syndrome - Wiskott-Aldrich syndrome protein binding inhibits tyrosine protein kinases
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