Hematology
Negative selection augments the characterization of bone marrow derivatives
Published in Blood Weekly, October 2nd, 2003
"Mesenchymal stem cells (MSCs) are typically enriched from bone marrow via isolation of the plastic adherent, fibroblastoid cell fraction. However, plastic adherent cultures elaborated from murine bone marrow are an admixture of fibroblastoid and hematopoietic cell types. Here we report a reliable method based on immunodepletion to fractionate fibroblastoid cells from hematopoietic cells within plastic adherent murine marrow cultures," scientists in the United States report.
"The immunodepleted cells expressed the antigens Sca-1, CD29, CD44, CD81, CD106, and the stem-cell...
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Source: Blood Weekly (2003-10-02)
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