Transplant Medicine
Complement from renal allograft tubules may play largest role in rejection
Published in Blood Weekly, October 9th, 2003
According to published research from England, "The role of innate immunity in allograft injury is just beginning to become clear, and complement is probably one of a number of factors that are activated very early in the course of transplantation.
"Kidney transplantation into complement-inhibited rats reduces subsequent inflammation of the graft, probably as a result of reduction of ischemia reperfusion damage as well as diminution of immune mediated damage. Closer analysis of the role of locally synthesized components in mice has suggested that...
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Source: Blood Weekly (2003-10-09)
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