T-Cell Activator
Preproenkephalin production by immune cells boosts T-cell activation
Published in Blood Weekly, October 16th, 2003
According to recent research from New Zealand, "Certain forms of the neuroendocrine hormone preproenkephalin (PPNK) are produced by T cells, B cells, and macrophages. This hormone has been shown to be important in regulating a variety of immune responses; however, the basic mechanisms of this regulation are unknown.
"Here we examine the ability of CD8 and CD4 PPNK-deficient T lymphocytes to proliferate to antigenic and mitogenic stimuli. We found that lymphocyte activation and proliferation to suboptimal concentrations of both anti-CD3...
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Source: Blood Weekly (2003-10-16)
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