Ligneous Conjunctivitis

Contraceptive pills can raise plasminogen in women with hypoplasminogenemia

Published in Blood Weekly, October 23rd, 2003

Oral contraceptives can raise the levels of plasminogen in women with congenital hypoplasminogenemia, as was found in patients with ligneous conjunctivitis.

"Severe type I plasminogen deficiency is the underlying cause of ligneous conjunctivitis, a rare disease characterized by wood-like pseudomembranes developing on the ocular and extraocular mucosa. Two unrelated female patients with ligneous conjunctivitis and moderate hypoplasminogenemia are described. Being of fertile age, they were treated with oral contraceptives, which determined a marked increase in plasminogen levels," scientists writing in the journal Thrombosis and Haemostasis report.

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Source: Blood Weekly (2003-10-23)

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