Susan Hasty, Publisher
Table of Contents . . . October 30th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Stem-Cell Transplantation - Costimulation blockade induces hematopoietic chimerism, central tolerance in SCT patients
Stem-Cell Transplantation - Rituximab active against refractory chronic GVHD
Myeloma Therapy - Treosulfan shows promise for multiple myeloma treatment
Stem-Cell Research - A58 oncogene can immortalize hematopoietic cells
Stem-Cell Research - Hematopoietic and mature blood cells can differentiate into cardiomyocytes
Transfusion Medicine - Dipyridamole improves efficacy of plasma exchange in TTP patients
Anthrax - $3.5M grant from U.S. government used for drug to treat anthrax exposure
Asthma - Late asthma may be calmed by cyclosporin A; it eliminates Bcl-2 pos T cells
Autoimmune Disease - Normally, autoantibodies produced by B cell precursors are eliminated at checkpoints
Biosafety - University receives $18M for construction of biosafety facility
Blood Analysis - Medical device manufacturer closes blood analysis product line acquisition
Blood Coagulation - Protease-activated receptor-1 agonists mimic angiogenic activation
Blood Products - Prestorage leukocyte reduction advised for autologous donation
Blood Substitute - Oxygen binding of cross-linked bis-hemoglobins evaluated
Blood Testing - Serologic T. cruzi test suitable for field, blood bank use
Cancer Therapy - Panzem formulation selected enhances bioavailability
Cardiology - Fusion between recipient- and donor-derived cells is a rare occurrence
Chronic Kidney Disease - New guidelines on bone disease in CKD address deficiencies
Colorectal Cancer - InSure test significantly increases patient participation in screening
Cord Blood - Biotech company receives cord blood to enhance stem-cell expansion technology
Deep Vein Thrombosis - ActiveCare DVT System now available
Dendritic-Cell Activation - CD1 and MHC-II molecules are in mature DC, despite lysosome reorganization
Dendritic-Cell Formation - TNF controls monocyte differentiation; dendritic cells form versus macrophages
Dengue Fever - Dengue fever outbreak occurs in Palau, Western Pacific
Environmental Health - Polybrominated and polychlorinated compounds found in human breast milk
Finance - Reagent company earns $3.7 million in net income in first quarter
Gene Transfer - GPI-anchored TFPI-1 alters tissue factor induced coagulation
Heart Disease Initiatives - Commission launches new research projects to combat cardiovascular disease
Heart Failure - Blood volume analyzer purchased by New York medical center
Heart Transplant Risk - A regimen without prednisolone in heart transplant may lower bone disease
Hematology - Bone marrow angiogenesis is implicated in hairy cell leukemia progression
Hematology - Brain morphogenetic gene Otx1 plays unexpected role in hematopoiesis
Hematology - Glycosylation restores survival of chilled blood platelets
Hematology - Oxidized low-density lipoprotein stops VEGF-induced cell differentiation
Hematology - Platelet proteinase-activated receptors play a significant role in tumor growth
Hematology - Pro- and anticoagulant proteins decreased during childhood
Hematology - The cdx4 gene specifies hematopoietic cell fate
Immunology - Paper highlights preclinical results of HIV peptide vaccine
Infection - StaphVAX confirmatory-phase-III trial ahead of schedule
Leukemia - Gene profiling may lead to customized treatments for pediatric patients
Leukemia - New studies examine racial differences and outcomes for children
Lithium Test - FDA clearance granted to market InstaRead rapid test for psychiatric use
Liver Failure - Bioartificial liver support systems bridge the transplantation gap
Liver Failure - The premise of adoptive immunity via transplantation needs more exploration
Malaria Therapy - Paroxysm serum from P. vivax infection blocks P. falciparum maturation
Menorrhagia - Desmopressin may not increase local fibrinolytic activity during menstruation
Multiple Myeloma - Agreement reached on STR phase III registration trial
Multiple Myeloma - Proteasome inhibitors suppress IRE1alpha, lower XBP-1, leading to apoptosis
Multiple Myeloma - Therapeutic implications of apoptotic signaling in multiple myeloma reported
Obstetrics - Alloimmune thrombocytopenia can be detected and even treated in utero
Oncology - Genes on 17q may be involved in the pathogenesis of classical Hodgkin lymphoma
Orthopedics - Grant will further research on healing bone injuries
Patents - Biotechnology corporation granted patent for gene delivery technology
Personnel - Spence Young named as director of reimbursement and national accounts
Prenatal Testing - Company announces milestone in development of noninvasive Down syndrome test
Recall - Nationwide recall issued for device used to determine blood-clotting time
Regulatory T-Cell Deficiency - Foxp3 is the gene critical for development of regulatory T cells
Relocation - Biotech contract-research organization moves headquarters to Colorado
Renal Transplantation - Nonmitogenic CD3 antibody can be used to treat acute kidney allograft rejection
Stem-Cell Research - Embryonic stem cells produced via nuclear transfer of human somatic nuclei into rabbit oocytes
Stem-Cell Research - HOXB4 increases cell regeneration after in vivo stem-cell selection
Stem-Cell Research - MyoR inhibits embryonic cell differentiation
Stem-Cell Research - Overexpressed hepatocyte growth factor treats the heart following ischemia
Stem-Cell Research - Positional identity gene expression codes not preserved in cultured neural stem cells
Stem-Cell Research - SDNSF helps maintain lifelong neurogenesis
Stem-Cell Research - Use eggs, not embryos, to derive stem cells, say researchers
Stem-Cell Research - WiCell earns national designation
Stem-Cell Transplantation - HLA class I and II typing may improve SCT outcome
Stem-Cell Transplantation - SCT schedule affects post-transplant T-cell repertoire
Systemic Lupus Erythematosus - Lower TCR zeta-chain in SLE is due to alteration, reducing the halflife
T-Cell Adhesion - Attachment of T cells to collagen is altered by lovastatin, phospholipase C
T-Cell Attachment - CD28 and small Rho GTPase Cdc42 are involved in actin rearrangement by T cells
T-Cell Differentiation - Repressor of GATA may be involved in differential development of Th2, Tc2 cells
Thromboembolic Disease - Protein C pathway in infants and children reviewed
Toxicology - Acetaminophen restriction curbs new emergency liver transplants in the U.K.
Transdifferentiation - Stem cell versatility questioned
Transfusion Medicine - Internet-based global apheresis registry initiated
Transfusion Medicine - MDS Nordion licenses x-ray blood irradiation technology
Transplant Medicine - Spleen transplantation may induce tolerance, but GVHD can occur too
Transplantation - Interferon therapy prior to liver transplant curbs hepatitis C recurrence
Virology - The 5' untranslated region of GB virus C highlights genotypic differences
West Nile Virus - Most patients with West Nile virus encephalitis responded rapidly to ARB
West Nile Virus - Season saw screening weaknesses, a rash of polio-like cases
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