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Heart Transplant Risk

A regimen without prednisolone in heart transplant may lower bone disease

Published in Blood Weekly, October 30th, 2003

A regimen without prednisolone in heart transplant may have lower bone disease risk if lower osteopenia, osteoporosis, and serum beta-CrossLaps are indicative.

According to published research from Austria, "Post-transplantation bone disease is a frequent problem after successful cardiac transplantation. We performed a cross-sectional analysis of male heart transplant recipients in the late post-transplantation period. Nine patients (group A) had received immunosuppressive therapy with cyclosporin A and mycophenolate mofetil (steroid-free treatment), and 12 patients (group B) remained on triple-drug therapy, which included glucocorticosteroids.

"Bone...

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