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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . November 13th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Stem Cells - Scientists find genetic "fountain of youth" for adult hematopoietic cells

Umbilical Cord Blood - Cord blood mast cells release I-309 after IgE exposure

DNA Research - Real-time PCR aids HIV DNA quantification

Liver Transplantation - CVVHD doesn't alter tacrolimus levels in recipients of small-for-size liver grafts

Stem-Cell Research - Multipotent, self-renewing cardiac stem cells identified

Transfusion Medicine - High-throughput NAT screening of donated blood in Japan reviewed

AIDS Testing - Medical Services to participate in live testing with the military in China

Anti-inflammatory Effects - Probiotic bacterial homogenates have antiproliferative effects on active PBMC

Asthma Drugs - Montelukast increases phagocytosis, intracellular killing by PML in asthmatics

B-Cell Immortalization - Epstein-Barr virus can be used to effectively immortalize human B lymphocytes

Beryllium Disease - Blood memory T cells are dependent, lung independent of CD28 costimulation

Biotechnology - Factor XIII improves performance of fibrin sealants

Blood Analysis - Medical College of Ohio obtains BVA-100 for organ transplant program

Blood Banking - Global Med, Gambro collaborate to optimize automated blood collection

Blood Counts - New high-performance hematology analyzer launched

Blood Oxygen - FDA issues 510-k approval for hand-held pulse oximeter

Blood Product Safety - International bioethics advisory council created

Burkitt Lymphoma - Surgery may have role in intra-abdominal Burkitt lymphoma in children

Cerebral Amyloid Angiopathy - Spontaneous hemorrhage in aging CAA patients may be due to MMP-9

Cerebral Ischemia - Stroke induces immunodeficiency, infections; various treatments prevent them

Coagulation - Proteinase-activated receptors can be activated by coagulation proteinases

Collaborations - Bayer Diagnostics selected to provide blood gas systems

Collaborations - Stem cell technology acquired

Corporate Restructuring - Development efforts refocused on pathogen inactivation, vaccines

Crohn Disease - Hematopoietic stem-cell transplantation is option for patients with severe CD

Demyelinating Disease - Chronic inflammatory demyelinating polyneuropathy may be treatable with IVIg

Demyelinating Polyneuropathy - CIDP with a low response to therapy may have other underlying disease or cancer

Dermatology - Cutaneous manifestations can initiate Waldenstrom macroglobulinemia

End-Stage Renal Disease - Company receives CE Mark approval for the OLpur MD 190

Finance - Blood analysis systems company reports conversion of stock

Finance - Blood substitute company reports first quarter financial results

Finance - Company reports increased revenues for third quarter of 2003

Finance - Stem cell banking company reports $0.08 per share loss

Genetic Disorders - Bone marrow transplantation resolves canine CLAD

HIV Prevention - U.S. agency opens Beijing office to help fight AIDS amid new candor by China

HIV/AIDS - Reticulated platelet assay helps identify HIV-related ITP

Hematology - Platelet aggregation reduction not mediated by lysine-binding regions

Hematology - Thrombin and platelet activation reviewed

Hemolytic Activity - Atlantic halibut and sea bass serum are capable of hemolyzing blood

Hemophilia A Therapy - Addition of a disulfide bond to factor VIIIa prolongs its life in blood

Henoch-Shonlein Purpura - Immunoglobulin A1 multiple myeloma patients can get Henoch-Schonlein purpura

Immune Modulator - Proteinase-activated receptors have many roles when on immune cells, fibroblasts

Influenza - Influenza-associated encephalopathy may be linked to cytokine transcription

Inherited Disease - Thrombocytopenia appears to be linked to chromosome 22q11.2 deletion syndrome

Innate Immunity - Toll-like receptors are targets for immunomodulating innate immunity disorders

Leukemia - CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells

Leukemia - Children's hospital has equal cure rates in black and white leukemia patients

Leukemia - Course of chronic myeloid leukemia in the elderly is not different

Leukemia Therapy - MEN 11079 shows promise as antileukemic agent

Leukemia Therapy - Novel assay may improve post-SCT immunotherapy for relapsed leukemia

Lipid Studies - Ganglioside uptake by leukocytes may lead to impaired cellular immunity

Malaria Diagnosis - QT-NASBA assay suitable for laboratory malaria screening

Mathematical Modeling - Limiting diversity of antigen presentation appears to enhance immune efficacy

Medical Errors - Iowa University Hospitals wants rebuild public trust

Myocardial Infarction - Study: Expanded population of cord-blood stem cells may treat heart disease

Non-Hodgkin Lymphoma - Capital investment to be used in part for cancer vaccine development

Patents - Patent approved in Japan for bone graft substitute

Placental Enzymes - AMP-deaminase from human placenta appears to be the same as the one from liver

Plasma Registry - French plasma exchange system monitors use, complications, permits studies

Platelet Functions - There may be links between inflammation, platelet function, and thrombosis

Proteomics - Cryoglobulinemia is a common disorder in those with chronic hepatitis C

Septicemia - Septicemic lymphopenia is due to Th1 cell apoptosis, creating a shift to Th2

Serum Proteins - Secreted CD155 can have a liver origin, may be involved in antiviral defense

Stem Cells - Bone marrow fusion with nerve cells may repair damage

Stem Cells - Researcher reports on new embryonic stem cell medium

Stem Cells - Researchers identify "niche" for hematopoietic cells

Stem-Cell Research - Advantages of 3D stem-cell coculture system clarified

Stem-Cell Research - Cultured stem cells from the adult brain develop into functional neurons

Stem-Cell Research - Early-born neurons derived from late retinal progenitors

Stem-Cell Research - Flow cytometry useful for identifying CNS stem cells in culture

Stem-Cell Research - Marrow-derived CMG cell line can become cardiomyocytes in vitro

Stem-Cell Research - Monoclonal antibodies useful for mapping receptor expression by hematopoietic cells

Stem-Cell Research - Mutant embryonic stem cells used to develop AD model

Stem-Cell Research - Myostatin sustains satellite cell quiescence

Stem-Cell Research - Transcriptome analysis sheds new light on stem-cell development

Stem-Cell Research - Transduced progenitor cells give rise to ones that express recombinant protein

Stem-Cell Research - Transfection of neurotrophic factor augments GSC expansion

Stem-Cell Transplantation - Cord blood CD34+ and CD133+ cells can be efficiently expanded in vitro

Stem-Cell Transplantation - Crystal violet with Merocyanine 540 can be useful for ex vivo stem-cell graft purging

Streptococcal Risk - Parkinson disease symptoms may occur following streptococcal pharyngitis

Telemedicine - Genesis is company's newest at-home telehealth monitor

Testicular Cytokine - Granulocyte-macrophage colony stimulating factor affects sperm motility

Transfusion Medicine - Belmont Instrument Fluid Management System (FMS 2000) suitable for rapid infusion

Transfusion Medicine - Refrigerating transfusion blood induces apoptosis, may cause immunosuppression

Transplantation - Kidneys from hepatitis C virus positive donors don't alter 1-year outcomes

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