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Anemia Therapy

Darbepoetin alfa is novel erythropoiesis-stimulating protein

Published in Blood Weekly, November 20th, 2003

Darbepoetin alfa is a novel erythropoiesis-stimulating protein.

"Darbepoetin alfa is a novel erythropoiesis-stimulating protein developed for the treatment of anemia. It is a hyperglycosylated analog of recombinant human erythropoietin with the same mechanism of action as erythropoietin, but with a three-fold longer terminal half-life after intravenous administration than recombinant human erythropoietin and the native hormone both in animal models and in humans," a scientist in Spain reports.

"Clinical studies in patients with chronic renal failure either receiving or not receiving dialysis have shown that darbepoetin alfa is equivalent to...

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