Susan Hasty, Publisher
Table of Contents . . . November 27th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Multiple Myeloma - Recombinant erythropoietin enables stem cell autografting without RBC transfusions
Stem-Cell Transplantation - Granulocyte transfusions can prevent post-SCT infections
Hematology - Superparamagnetic labeling enables stromal cell tracking
Multiple Myeloma - Ho-166-DOTMP with stem-cell autografting shows promise against MM in early studies
Multiple Sclerosis - Immunosuppression therapy with stem-cell transplant ineffective in severe progressive MS
Stem-Cell Transplantation - Infliximab shows promise for treatment of gastrointestinal GVHD
AIDS Co-infections - Data: Hepsera associated with sustained reductions in hepatitis B virus
Allergy Medicine - Aqueous extract of Xanthii fructus may calm mast cells, stop anaphylaxis
Antigen Presentation - Polymorphonuclear neutrophils have many functions including antigen presentation
Awards - NewsRx wins 2003 eHealthcare Leadership awards
Biclonal T-Cell Expansion - Monoclonal EBV infects T cells, expands one or more clones in active infection
Bioengineering - Heparin and alginate crosslinked gel microparticles stimulate remodeling
Blood Clotting Disorders - FDA clears 11 diagnostic tests for risk of cardiovascular disease
Chemical Sensitization - Epidermal Langerhans cells induce chemical sensitization; under cytokine control
Cirrhosis - Hepatitis C virus reinfection speeds rejection after liver transplantation
Collaborations - $90M hematology agreement signed
Corporate Update - Gene therapy company reports on drug development, finances
Dendritic Cell Maturation - Viral infection or dsRNA induce specific maturation pathways in dendritic cells
Dermatology - Endemic pemphigus foliaceus patients have a Th2 bias and high IL-1 production
Diabetes Medicine - Blood cells that are CD34+ help diabetic mouse skin wounds to heal faster
Diagnostics - Thymocyte populations can be analyzed for all nuclear proteins by flow cytometry
Echocardiography - Atrial thrombosis can be slowly resolved without embolism by warfarin, aspirin
Environmental Health - Vanadium(IV) tetraoxide has genotoxic effects on peripheral blood cells
Fetal Immune System - Human fetus has active immune system and unique CD95-CD45RO+ T-cells
Finance - Blood systems developer reports loss of $0.64 per share
Finance - Testing products company reports 22% increase in revenues during third quarter
Hematology - C-type lectin from venom of Crotalus durissus terrificus characterized
Hematology - Thrombophilia and venous thromboembolism warrant therapy in pregnant women
Hepatitis B - Positive 1-year data on telbivudine presented for the treatment of chronic HBV
Hepatitis B - Prophylactic therapy makes renal transplantation safe for hepatitis B patients
Hepatitis C - Positive data reported on IDN-6556 for liver impairment in HCV patients
Hepatitis C - Study investigates Pegasys and Copegus in African Americans
Hepatitis C - Study shows benefits of therapy in previously under-treated patient population
Immunogenicity - Therapeutic biologicals must be developed without unwanted immunogenicity
Immunology - Genzyme enters joint effort to develop therapies for immune-mediated diseases
Immunology - Higher steroid doses improve liver function during acute rejection episodes
Immunology - Monocytes can be separated from buffy coats following a simple three-step method
Insect-borne Disease - Trypanosoma cruzi, T. rangeli is distinguishable by PCR in human, insect
Kidney Disease - Nationwide screening reveals high kidney disease rates, low awareness level
Leukemia - Comprehensive gene profiles hold promise for improving outcomes
Leukemia - Scientists identify enzyme with key role in leukemia protein's normal function
Leukocytes and Cannabinoids - Polymorphonuclear leukocytes don't have receptor nor respond to cannabinoids
Liver Repair - The complements C3a and C5a appear to be necessary for liver regeneration
Liver Transplantation - Living liver donors increase the risk for cholestasis in graft recipients
Lung Transplants - Modified lung donor standards increase donor pool, decrease mortality
Lymphadenitis - Histiocytic necrotizing lymphadenitis is a common occurrence, not well studied
Lymphoma - Murine model of human anaplastic large-cell lymphoma developed
Lymphoma Therapy - High-dose radioimmunotherapy may be superior to standard follicular lymphoma treatment
Lymphoma Therapy - Posttransplant HHV8 infection remains a problem for bone marrow graft recipients
Melanoma - Antiplatelet drug blocks bone tumor metastases in mice
Multiple Sclerosis - Gelatinase B/MMP-9 produces an antigenic peptide from alpha B-crystallin
Multiple Sclerosis - Myelin oligodendrocyte glycoprotein, an MS autoantigen, is in dimer form
Myocardial Infarction - Bone marrow stem cells can reduce ischemia-induced cardiac damage
Natural Killer Function - NKT cells react to glycolipids by downregulating surface receptors, expanding
Nonmyeloablative Transplant - Pentostatin appears to induce safe lymphodepletion for stem-cell transplant
Obstetrics - Oxytocin in prefilled injection devices is convenient for home deliveries
Occupational Health - Aerosols generated during dental debonding may transmit hepatitis B infection
Oxygen Therapeutic - Company to respond to FDA's questions on Hemopure
Psychiatric Disorders - Prevalence of antibodies to neurotransmitter receptors may affect mental health
Psychiatric Pseudoinfection - Clozapine therapy can cause inflammation, possible Ig-mediated hypersensitivity
Pulmonary Inflammation - Peripheral benzodiazepine receptor ligands appear to benefit pneumopathy
SARS - Severe acute respiratory syndrome produces lymphopenia, immunodeficiency
Staphylococcus Aureus - S. aureus may affect Wegener granulomatosis through lymphoid interactions
Stem-Cell Research - A functional assay for epidermal stem cells should open up research options
Stem-Cell Research - Akt signaling regulates side population cell phenotype through Bcrp1 expression
Stem-Cell Research - FLIP prevents apoptosis in quiescent erythroid progenitors
Stem-Cell Research - Human stem cell work may start in 5 years
Stem-Cell Research - Recombinant SCF used to identify c-kit+ porcine marrow progenitors
Stem-Cell Research - Researcher to make 17 new cell lines available to research community
Stem-Cell Transplantation - Dendritic cell function impaired after reduced-intensity conditioning
Stem-Cell Transplantation - Post-SCT calcineurin inhibitor-induced CNS toxicity has poor long-term outcome
Stem-Cell Transplantation - Quantitative real-time PCR improves post-SCT CMV detection
Supply Agreements - Antibody-manufacturing agreement signed with BioE
T-Cell Subsets - Ionomycin-resistant, CD4+ T cell subset in PBMC may be multidrug resistant
Thrombocytopenia Purpura - Anti-idiotypic antibodies to antiplatelet antibodies are common in idiopathic TP
Transfusion Medicine - Endothelin-1 reverses hemorrhagic hypotension in rats
Transfusion Medicine - Intraoperative autologous transfusion device expensive but ineffective
Transfusion Safety - Strategic alliance to market Donor-ID and Transfuse-ID
Transplant Medicine - Daclizumab, tacrolimus, and mycophenolate mofetil are safe for second transplant
Transplant Medicine - Donor-transmitted malignancy highlights a need for organ procurement vigilance
Transplant Medicine - Large B-cell malignancy, Castleman disease involve HHV-8, EBV post-transplant
Transplant Medicine - Piggyback transplant involving liver may risk post-transplant pulmonary embolism
Transplant Medicine - Post-transplantation lymphoproliferative disorders are mostly caused by EBV
Transplant Medicine - Sensitive PCR assay will allow monitoring of human herpesviruses 6A, 6B, and 7
Transplant Research - Ethylcarbodiimide-treated dendritic cells prolong organ graft survival
Tuberculosis Diagnostics - Blood culture suitable for diagnosis of disseminated TB
Ubiquitination Disorder - TNF-alpha controls NEMO ubiquitination; NEMO zinc finger mutation alters this
Vaccine Safety - Recommended immunization of patients with bleeding disorders outlined
West Nile Virus - West Nile encephalitis reported in two hematopoietic stem-cell graft recipients
Women's Health - Immunoglobulin-secreting cells are more frequent during the periovulatory stage
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