Wound Healing
Heparin cofactor II, antithrombin III have separate localization in skin wounds
Published in Blood Weekly, December 11th, 2003
According to recent research from the United States, "the physiologic function of the serpin heparin cofactor II (HCII) is not fully understood. We have hypothesized that HCII functions as an extravascular inhibitor of thrombin. Thrombin formed at a site of injury has been hypothesized to contribute to migration and proliferation of fibroblasts and smooth muscle cells involved in wound healing.
"To begin to test our hypothesis, we examined the immunohistochemical localization of HCII in human skin, and compared it to that of the closely...
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Source: Blood Weekly (2003-12-11)
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