Blood Weekly

Immunosenescence - CD8+ T cells may have higher levels of internal cytokines as humans age

Immunotherapy - Risks associated with use of intravenous immunoglobulin reviewed

Infectious Disease - Serum albumin level linked to HFRS severity

Inflammation - Macrophages oxidize ECM; LPS, IgG increases effect, dexamethasone lowers it

Kidney Cancer - Bone marrow transplant program offers "mini-transplant"

Kidney Disease - Aranesp maintains hemoglobin levels

Kidney Transplantation - West Nile virus-associated meningoencephalitis is a risk after kidney transplant

Leukemia Therapy - BACH2 expression can augment the cytotoxic effects of anticancer agents

Leukemia Therapy - Loss of post-SCT immune VZV control and leukemia relapse may be linked

Leukemia Therapy - Use of immunoregulatory cells in stem cell transplantation reviewed

Lymphocyte Disorders - DOCK2 mediates Rac activation after binding ELMO1; may be a target for therapy

Lymphocyte Transmigration - Junctional adhesion molecules may be involved in leukocyte transmigration

Lymphoma - Third phase II trial initiated for new stem-cell transplantation drug candidate

Multiple Myeloma Therapy - High-dose VAD with auto-SCT effective for acute MM patients

Multiple Sclerosis - CD8+ T cells in MS types are correlated to adverse MRI lesion load features

Neurological Disease - Serum anti-Fas antibody levels aren't specific for amyotrophic lateral sclerosis

Neuromuscular Disease - Lack of dysferlin gives high MHC-I, macrophage; no cytotoxic T cells in muscle

Oncology - Injecting tumors with CpG-oligodeoxynucleotide promotes antitumor response

Prognostic Modeling - Immunosuppressive therapy response in myelodysplastic syndrome is predictable

Psychology - Atopic dermatitis can be caused by psychological stress; immunity is altered

Renal Disease - Company presents results linking antibodies to dsDNA with renal flares

Rheumatoid Arthritis - Combination therapy with low dose glucocorticoids may benefit early arthritis

Stem Cell - Company announces development of defined culture medium for hESC propagation

Stem-Cell Research -  Dicer plays essential role in embryonic mouse development

Stem-Cell Research - Cell fusion: an alternative to stem-cell plasticity?

Stem-Cell Research - Emu-GFP-3'LCR transgene forces B lineage expression

Stem-Cell Research - Mesenchymal stem cells can differentiate into neuron-like cells in vitro

Stem-Cell Research - Neural stem-cell self-renewal - unlike progenitor proliferation - is Bmi-1 dependent

Stem-Cell Research - Neuronal precursors can differentiate into astrocytes

Stem-Cell Research - Possible embryonic liver progenitor cells identified

Stem-Cell Transplantation - Cytomegalovirus prophylaxis for allo-SCT recipients reviewed

Stem-Cell Transplantation - First case of DLI-linked nephrotic syndrome described

Stem-Cell Transplantation - Late post-SCT diversification of CMV-specific CD8 cells possible

Stem-Cell Transplantation - Safety and efficacy of nonmyeloablative SCT reviewed

Targeted Therapy - T-cell adaptor proteins may be useful targets for transplantation, leukemia

Thrombophilia - Oral contraceptives and the factor V Leiden mutation increase thrombosis risk

Transfusion Medicine - Antibody screens for Mongoloid populations should include Di(a) panel cells

Transplant Medicine - C4d complement split product in peritubular capillaries is a sign of rejection

Transplant Medicine - Serial serum protein electrophoresis can be used to monitor PTLD following transplantation

Transplantation - De novo non-alcoholic fatty liver disease forms in liver transplant recipients

Transplantation - Liver transplantees older than 60 have reduced survival and more cancer

Trypanosoma Cruzi -  T. cruzi meningoencephalitis may be inhibited by anti-VLA-4 Ab

West Nile Risk - West Nile virus can cause death, no IgM, in bone marrow transplant recipients