Cytotoxicity
Cytotoxic lymphocyte cytotoxicity can be measured using an anti-caspase 3 assay
Published in Blood Weekly, December 18th, 2003
According to recent research from the United States, "CTLs are critical effector cells of the immune system. Measurement of target cell damage has historically been an important measure of CTL function.
"CTLs kill their target cells predominantly by inducing programmed cell death, or apoptosis. The gold standard for CTL-mediated cytotoxicity has been the 51Cr release assay. However, measurement of target cell lysis by 51Cr release does not provide mechanistic information on the...
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Source: Blood Weekly (2003-12-18)
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