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Hematology

ABO blood type and race affects von Willebrand factor activity

Published in Blood Weekly, December 18th, 2003

ABO blood type and race affects the measurement of von Willebrand factor activity.

According to recent research published in the Journal of Thrombosis and Haemostasis, "Tests based on three different principles are reported to measure the activity of von Willebrand factor (VWF): ristocetin cofactor (VWF:RCo), collagen binding (VWF:CB), and the so-called 'activity ELISA' (VWF:MoAb). We measured these and other diagnostic parameters in a population of 123 randomly selected female study controls, age 18-45 years."

"Type O subjects had significantly lower levels than non-O subjects in each test," reported Connie H. Miller and collaborators at the...

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