Stem-Cell Research
Cripto signaling plays key role in embryonic cardiomyogenesis
Published in Blood Weekly, December 25th, 2003
According to recent research from Italy, "The molecular mechanisms controlling inductive events leading to the specification and terminal differentiation of cardiomyocytes are still largely unknown."
S. Parisi and coauthors at the Consiglio Naziolale delle Ricerche in Naples "investigated the role of Cripto, an EGF-CFC factor, in the earliest stages of cardiomyogenesis."
"We find that both the timing of initiation and the duration of Cripto signaling are crucial for priming differentiation of embryonic stem (ES) cells into cardiomyocytes, indicating that Cripto acts...
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Source: Blood Weekly (2003-12-25)
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