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Allergic Rhinitis

Repeat rhinitis therapy with omalizumab is safe for a second ragweed season

Published in Blood Weekly, January 8th, 2004

Repeat rhinitis therapy with omalizumab is safe for a second ragweed pollen season.

"Two randomized, placebo-controlled, double-blind studies have shown clinical benefit with omalizumab (Xolair), a recombinant humanized monoclonal anti-immunoglobulin E (IgE) antibody, at a dose of 300 mg every 3-4 wks in patients with seasonal allergic rhinitis," investigators in the United States report.

"The present open-label, 12-week study was designed to assess the safety and tolerability of retreatment with omalizumab in 287 patients previously treated with this agent in one of the latter studies. Omalizumab, 300 mg, was administered subcutaneously every 4...

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