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Multiple Sclerosis

Genomics research reveals 10 genes associated with multiple sclerosis

Published in Blood Weekly, January 22nd, 2004

A whole genome screen has revealede 10 genes associated with multiple sclerosis (MS).

According to recent research from Portugal, "MS is common in Europe, affecting up to 1:500 people. In an effort to identify genes influencing susceptibility to the disease, we have performed a population-based whole genome screen for association.

"In this study, 6000 microsatellite markers were typed in separately pooled DNA samples from MS patients (n=188) and matched controls (n=188)," wrote M. Santos and colleagues.

The researchers concluded: "Interpretable data was obtained from 4661 of these markers. Refining analysis of the most promising...

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