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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . January 29th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Cancer Therapy - Endurance training can preserve fitness during chemotherapy+SCT

Awards - Wilmot leukemia expert gets national achievement award

Bacterial Contamination - Technology licensed from Infectio for bacterial detection system for platelets

Cancer Therapy - IPSS score has limited prognostic value for MDS patients undergoing intensive treatment

Cancer Therapy - Treatment of post-HDC/HSCT infections reveiwed

Cell Biology - Cells' ability to open blood's floodgates hinges on unexpected factors

Cell Biology - ETH Zurich: New aspects in stem cell development discussed

Chagas Disease - Virulence factor identified

Chlamydia Pneumoniae -  C. pneumoniae may play a role in CNS diseases such as Alzheimer and MS

Cryopreservation - Cord blood bank in Turkey orders BioArchive Systems

Finance - StaphVAX maker completes common stock offering

Stem-Cell Transplantation - Auto-SCT complications more extensive during hematological cancer

Genetic Disorders - Novel alpha-thalassemia mutations identified

Geriatrics - Thymic stromal macrophages and dendritic cells are not greatly altered with age

Helicobacter Pylori - Pediatric H. pylori Cag A total IgG, IgG subclass, indicate pathology type

Hematological Cancer - Features of leukemic involvement in ALCL described

Hematology - Mini-adenoviral vector extends clotting factor production in hemophilia models

Hematology - Potent, selective, and orally bioavailable factor Xa inhibitor developed

Hemophilia - Intracranial hemorrhage treatment for hemophiliacs reviewed

Hepatitis C Virus - Study shows progression is mild over 35 years after infection in infanthood

Hemophilia - ADHD common in young male hemophiliacs

Hypertension - Hypotensive effects of cerebral Ang-(1-7) evaluated in rat hemorrhage model

Immune Evasion - Tumors induce type II polarized macrophages that aid in tumor progression

Immunology - Lipopolysaccharide needed for efficient DC maturation in MCM culture

Influenza Virus - Outer membrane protein A and influenza hemagglutinin fusion domain described

Leukemia - High-dose methylprednisolone induces remission in CLL patients

Leukemia Diagnostics - Wilms tumor 1 gene transcripts useful for measuring minimal residual disease

Liver Transplantation - Over-immunosuppression leaves transplanted cholangitis patients prone to cancer

Lymphocyte Activation - Apelin is involved in lymphocytic cholinergic activity in immune response

Lymphoma - CD5+ diffuse large-B-cell lymphoma has a poorer prognosis than CD5-lymphoma

Stem-Cell Research - Skeletal muscles have highly differential incorporation of marrow-derived cells

Lymphoma - Murine anaplastic large-cell lymphoma model developed

Lymphoma Therapy - High-dose radioimmunotherapy may be superior to standard lymphoma treatment

Mergers and Acquisitions - Oncology, hematology companies complete merger

Myasthenia Gravis - FcgammaIIA-R/R131 genotypic distribution is altered in myasthenia gravis

Natural Killer Function - NKT cells become activated, produce IFNgamma in response to CD1d antigen, IL-12

Neutrophil Function - Neutrophil degranulation is an essential part of the inflammatory reaction

Oncology - Complex interactions control endothelial cell proliferation and tumor apoptosis

Parasitology -  Opisthorchis viverrini is a fluke in raw fish that can infect human liver

Patient Education - New non-Hodgkin lymphoma treatment guidelines available

Personnel - Biotechnology company announces new chief financial officer

Stem-Cell Transplantation - Mycobacterial infection can cancel effects of SCT for IFMgammaR1 deficiency

Personnel - Canadian biopharma taps David Kinniburgh as VP

Regenerative Medicine - System for maintaining pluripotency in embryonic stem cells developed

Salt Exposure - Potassium salt exposure by female mineworkers, offspring does not alter immunity

Spleen Function - Beta-catenin is required at a checkpoint in spleen allowing T-cell development

Stem-Cell Research - Features of polycythemia vera reviewed

Stem-Cell Transplantation - Dendritic cell function impaired after reduced-intensity conditioning

Stem-Cell Transplantation - Epidemiology of infection following allo-SCT reviewed

Stem-Cell Transplantation - Quantitative real-time PCR improves post-SCT CMV detection

T-Cell Function - IL-2 is needed for the second part of T-cell generation, not initial expansion

Transplant Medicine - Sibling donates marrow to two other brothers

Stem-Cell Transplantation - Passenger lymphocyte syndrome possible in HLA-matched SCT

Tuberculosis Diagnostics - Blood culture suitable for diagnosis of disseminated TB

Angiology - Fibrosing mediastinitis, vena cava thrombosis can occur in Behcet disease

Angiology - Platelet-activating factor allows CD40 to trigger new vessel growth

Antibody Generation - IgA changes quantity from infancy to childhood; in saliva, serum, polymeric form

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