Immune Evasion
Tumors induce type II polarized macrophages that aid in tumor progression
Published in Blood Weekly, January 29th, 2004
"Environmental signals polarize mononuclear phagocytes that can express different functional programs. Fully polarized type I and type II (or alternatively activated) macrophages are the extremes of a continuum of functional states," scientists in Italy report.
"Tumor-derived and T cell-derived cytokines stimulate tumor associated macrophages (TAM) to acquire a polarized type II phenotype," wrote A. Mantovani and colleagues.
The researchers concluded: "These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumors,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2004-01-29)
More Articles from Blood Weekly
- Cancer Therapy
Endurance training can preserve fitness during chemotherapy+SCT - Awards
Wilmot leukemia expert gets national achievement award - Bacterial Contamination
Technology licensed from Infectio for bacterial detection system for platelets - Cancer Therapy
IPSS score has limited prognostic value for MDS patients undergoing intensive treatment - Cancer Therapy
Treatment of post-HDC/HSCT infections reveiwed - Cell Biology
Cells' ability to open blood's floodgates hinges on unexpected factors - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
