Leukemia Diagnostics
Wilms tumor 1 gene transcripts useful for measuring minimal residual disease
Published in Blood Weekly, January 29th, 2004
Researchers in England "developed a sensitive, competitive, nested reverse transcription polymerase chain reaction (RT-PCR) titration assay that quantifies the number of Wilm's tumor (WT1) gene transcripts in bone marrow (BM) and peripheral blood (PB), coupled with a competitive RT-PCR protocol for the ABL gene as control."
M. Garg and colleagues at the University of Manchester "studied BM/PB samples from 107 acute myeloid leukemia (AML) patients and 22 acute lymphoblastic leukemia (ALL) patients at presentation and detected the WT1 gene in...
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Source: Blood Weekly (2004-01-29)
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