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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . February 5th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Stem-Cell Transplantation - CD133-based stem-cell selection feasible with alternative donors

Aplastic Anemia - Th1 polarization underlies hematopoietic dysfunction in AAA patients

Cancer Therapy - Enrollment complete for phase II clinical study in non-Hodgkin lymphoma

Cancer Therapy - FLAG±Ida suitable for induction chemo in high-risk leukemia, MDS patients

Cancer Therapy - Granulocyte colony-stimulating factor reduces complications in elderly patients

Creutzfeldt Jakob Disease - Action needed to prevent spread of vCJD via blood

Environmental Health - Methemoglobin levels correlate with environmental exposures in pregnant women

Finance - Instrument-reagent company announces fiscal second quarter results

Gene Replacement - Ex vivo gene therapy rectifies Niemann-Pick disease in animal models

HIV/AIDS Diagnostics - Dried blood suitable for HIV diagnosis in the field

Heart Disease - Perfluorocarbon-based blood substitute to undergo phase II clinical testing

Stem-Cell Transplantation - Full peripheral blood RBC chimerism needed for SCD cure

Hematology - Erythropoietin amends therapy-induced anemia in patients with hepatitis C

Hematology - Integrin-ligand interactions synergize in arterial injury platelet adhesion

Hematology - Liver cancer rates parallel the aging of thalassemic populations in Italy

Hematology - Platelet-activating factor stops enzyme secretion in decidual macrophages

Hematology - Transduced stem cells hold the potential for correcting sickle cell disease

Infectious Disease -  H. pylori CagA mimicry may underlie cITP

Iron Overload - HFE gene mutations associate with fibrosis in chronic hepatitis C patients

Leukemia - Common clonal origin seen in twins with leukemia

Leukemia - Malignant stem cells express high levels of FGFR-3

Aplastic Anemia - HSCT safe and effective for Taiwanese SAA patients

Leukemia Diagnostics - LightCycler, TaqMan tests equally suitable for pediatric MRD measurement

Leukemia Diagnostics - MRP3 linked to drug resistance in pediatric ALL

Leukemia Diagnostics - ZAP-70 expression is a prognostic factor in CLL patients

Myelodysplastic Syndrome - Role of FLIP isoforms in apoptosis elucidated

Needle Safety - Safety blood collection needle product line launches in U.S.

Neonatal Tumors - An international working group reports on the epidemiology of neonatal tumors

Non-Hodgkin Lymphoma - Update provided on program evaluating Proleukin interleukin-2

Stem-Cell Research - Muscle-derived stem cells may have limited hematopoietic potential

Pediatrics - Children's hospitals across the U.S. are expanding

Pulmonary Fibrosis - Bone marrow-derived stem cells active in pulmonary fibrosis

Reproductive Medicine - Factor XIII A is essential for maintaining placental integrity

Severe Combined Immune Deficiency - Unusual leukemia caused by rare combination of genes

Sickle-Cell Disease - Clinical compound rPSGL-Ig licensed for development and commercialization

Stem-Cell Research - Acute myeloid leukemia fusion proteins deregulate maintenance and repair genes

Stem-Cell Research - Bax and Bak regulate size of neural stem-cell pool

Stem-Cell Research - Concepts of stem-cell plasticity reviewed

Stem-Cell Research - Hematopoietic progenitor subset expresses neural genes

Stem-Cell Research - Japanese university produces first human embryo stem cells for domestic research

Stem-Cell Transplantation - CMV-seropositive donors might be preferable for seropositive SCT recipients

Stem-Cell Research - Pathological links between PNH and aplastic anemia reviewed

Stem-Cell Transplantation - Impaired naive T-cell survival underlies post-SCT immunodeficiency

Toxicology - The cleaning solvent HCFC-141b produces genotoxic effects in rodents

Tuberculosis Diagnostics - PBMC-PCR can facilitate tuberculous lymphadenitis diagnosis

Stem-Cell Transplantation - High-level cryopreservation of mobilized PBSC feasible without programmed freezer

Adverse Drug Effects - Inorganic arsenic therapies may have toxic side effects

Adverse Drug Effects - Lamivudine prevents rituximab-induced hepatitis B virus reactivation

Anemia - Hemopure regulatory status updated following FDA meeting

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