Published in Blood Weekly, February 5th, 2004
"Immune dysfunction, which leads to the suppression of hemopoiesis by cytokines that are secreted by activated T lymphocytes, is considered to play a key role in the pathogenesis of acquired aplastic anaemia (AAA)," hematologists in Greece explained.
In a recent study, N.C. Giannakoulas and colleagues at the University Hospital in Patras "investigated the intracytoplasmic expression of type-1 [interferon gamma (IFN-gamma), interleukin (IL)-2] and type-2 (IL-4, IL-10) cytokines in CD4+ and CD8+ T cells before and after in vitro activation in 16 patients with AAA and 17 normal...
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