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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . April 8th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Stem-Cell Research - Podocalyxin-like protein may be useful as hematopoietic stem cell marker

Stem-Cell Transplantation - Young female bone marrow recipients have high risk of ovarian damage

Graft-versus-Host Disease - Twice-daily CsA prophylaxis more effective than continuous infusion

Renal Cell Cancer - IFN-producing cytotoxic T cells may mediate stem-cell graft-vs-tumor effect

Stem-Cell Transplantation - Lipid amphotericin B formulations protect post-HSCT renal function

Stem-Cell Transplantation - Recombinant G-CSF indirectly suppresses T-cell activity

Acute Myeloid Leukemia - Cloretazine receives Fast Track designation from FDA

Blood Transfusions - Positive phase Ib/II clinical trial results reported for Hemospan

Bovine Spongiform Encephalopathy - Britain restricts blood donations as a precaution against mad cow's disease

Business & Finance - Initial letter agreement announced for adult stem cell bank

Business Update - Company announces a new name for point-of-care blood-analysis system

Cancer Risk - Radiation after prostate cancer recurrence benefits high-risk patients

Cardiology - Everolimus may prevent rejection and vasculopathy after heart transplantation

Cardiovascular Disease - Juvenile and adult rabbits respond differently to homocysteine treatment

Cardiovascular Disease - Role of ABCA1 in cholesterol metabolism reviewed

Cardiovascular Disease Therapy - Plasmat Futura HELP apheresis system safe and effective

Cell Biology - Cells induced to "de-differentiate" back into stem cells

Chronic Hepatitis B - Hepatitis B core antigen makes T cells and monocytes secrete interleukin-10

Chronic Lymphocytic Leukemia - Preliminary results of Xcytrin for chronic lymphocytic leukemia announced

Complementary & Alternative Medicine - Alternative medicines can pose risks for cancer patients

Diabetes - Survey shows conservative voters support embryonic stem cell science

Drug Delivery - Novel hemoglobin-carrying nanoparticles developed

Finance - $10.4 million raised in private placement of common stock

Finance - Product candidate gets boost from $12.8 million private placement

Finance - Vaccine development helps drive company's 25% revenue increase in 2003

Heart Attack - Catheter-based delivery system deploys stem cells to heart attack patients

Heart Attack - Plasma lipids augment post-infarction erythrocyte aggregation

Hematologic Cancer - Lymphohematopoietic cancer may be related to Alachlor exposure

Hematology - Erythrocyte ghosts prolong plasmid DNA expression in the blood

Hematology - Fanconi anemia group C protein regulated through proteolytic modification

Hematology - Immunosuppressive therapy diminishes pancytopenia in a child with monosomy 7

Hematology - Novel thioredoxin-related protein expressed in plasma cells identified

Hematology - P-selectin modulation involved in hemostasis

Hematology - Previous Rh incompatible pregnancies raise schizophrenia risks in later births

Heparin - Heparin binds to the laminin alpha 4 chain LG4 domain at a unique site

Hepatitis B Virus - Nabi to supply Novaplus Nabi-HB

Immunology - Myeloperoxidase expression identifies acute myeloblastic leukemia variants

Immunology - The 4H84 mAb can bind to non-HLA-G molecules

Infection Control - A critical juncture for hemodialysis-related HCV passage is saline flushing

Leukemia - Combo of two natural toxins may be novel treatment for blood cancer

Leukemia - Failure of DNA repair mechanism precedes final stage of deadly leukemia

Mosquito-borne Disease - Replication kinetics of Chimerivax-DEN in Aedes aegypti determined

Multiple Myeloma Therapy - Busulphan-cyclophosphamide conditioning safe, effective for auto-SCT

Myelodysplastic Syndrome - Dacogen clinical study interim data clarification released

Myeloma - Simvastatin given with cytotoxic drugs is advantageous in myeloma cell lines

Myocardial Infarction - Stem cells not the cure for a broken heart

Obstetrics - Factor V gene polymorphisms leave Finnish women vulnerable to preeclampsia

Occupational Health - Doctors call for balancing of patient/worker viral transmission protection

Occupational Health - Some electric utility workers show reduced levels of immune system cells

Personnel - Biotechnology company announces new scientific advisor

Personnel - Former Mount Sinai doctor comes to Cleveland Clinic

Quality Assurance - Company announces an upgrade to ISO 9001:2000 certification

Radiology - MR imaging of toxoplasmosis encephalitis in BMT recipients characterized

Shwachman-Diamond Syndrome - Successful unrelated BMT reported in SDS patient with leukemia

Squamous Cell Carcinoma - Docetaxel, cisplatin and 5-FU are effective in squamous cell carcinoma

Staph Infections - Company initiates enrollment in phase II trial for Aurexis

Stem-Cell Research - BDNF gene-modified mesenchymal stem cells foster recovery after ischemic stroke

Stem-Cell Research - Muscle satellite cells and connective tissue can derive from transplanted BM cells

Stem-Cell Research - Novel anti-apoptotic molecule plays key role in hematopoiesis

Stem-Cell Research - Novel culture system efficiently produces eosinophils from embryonic cells

Stem-Cell Research - Pancreatic islet-derived stem cells can engraft and induce tolerance in mice

Stem-Cell Research - V(D)J recombinase activity elucidated

Stem-Cell Transplantation - MiniMACS system superior to Isolex 50 for CD34 cell selection

Stem-Cell Transplantation - Outcome of reduced-intensity conditioning evaluated

Toxicology - No dermal subchronic toxicity found for phenoxyethyl isobutyrate

Transfusion Medicine - Autologous MDS cells can reconstitute erythrocyte populations after DLI

Transfusion Medicine - Methylene blue virus photoinactivation reviewed

Transfusion Medicine - Public-private partnership to conduct radio frequency identification pilot study

Transplant Medicine - BK polyoma virus infection plagues renal transplant recipients in India

Transplant Medicine - Complement-related approaches diagnose antibody-mediated rejection

Transplant Medicine - Immune cells fight cancer's return, predict outcome after stem-cell transplant

Transplant Medicine - Plasma exchange techniques temporarily support liver transplant candidates

Transplant Medicine - Valaciclovir treats chronic hepatitis B after lung transplantation

cDNA Clones - GNF acquires TrueClone collection

von Willebrand Disease - Mutation disrupts interaction of von Willebrand factor with platelets

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