Hematology
Survivin suppression halts the growth of aggressive non-Hodgkin's lymphoma
Published in Blood Weekly, April 15th, 2004
According to published research from the United States, "survivin is a member of the inhibitor of apoptosis protein (IAP) family and functions both as an apoptosis inhibitor and a regulator of cell division. Survivin overexpression is common in many human tumors and correlates with survival in large cell non-Hodgkin's lymphoma. To evaluate this molecule as a potential therapeutic target in large-cell lymphoma, we evaluated the effect of survivin inhibition both in vitro and in vivo."
"Using an antisense oligonucleotide (ASO) approach, cell growth was significantly inhibited...
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Source: Blood Weekly (2004-04-15)
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