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Genomics

Company to provide Merck with genetic rat models

Published in Blood Weekly, April 29th, 2004

Ingenium Pharmaceuticals, AG, announced an agreement under which Ingenium shall seek to provide Merck & Co., Inc., (MRK) with novel genetic rat models with alterations in a gene specified by Merck.

No financial terms or further details of the agreement have been disclosed.

The models will be developed using Ingenium's INGENOtyping technology. As opposed to mouse "knockout" models, the development of genetic rat models remains a scientific hurdle despite years of intense research worldwide, due to the lack of rat embryonic stem cells. Nevertheless, the rat remains the model of choice for many therapeutic areas, including cardiovascular, behavioral,...

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