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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . May 6th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Artificial Blood - NO scavenging underlies hypertensive effects on Hb-based blood substitutes

Blood Banking - Decision support system developed for measurement of operational efficiency

Multiple Sclerosis Therapy - MRI-invisible brain tissue loss continues after stem-cell transplantation

Sickle Cell Anemia - Spectrin ubiquitination controls spectrin complex dissociation

Stem Cell Transplantation - IL-10-treated dendritic cells may induce GVHD risk

Acute Lymphoblastic Leukemia - Molecular analyses of ALL suggest strategies for more effective treatments

Angiology - Antioxidants may mediate exercise-induced drop in platelet activity

Atherosclerosis - Novel platelet proteins located in human atherosclerotic lesions

Blood Contamination - Sorority apologizes after urging members to lie for blood drive

Breast Cancer - HCCR-2 related to breast cancer development and p53 tumor suppressor regulation

Breast Cancer - Lymphatic mapping suggested when invasive breast cancer is suspected

Business & Finance - Strategic alliance announced by biopharmaceutical company

Cancer Therapy - Microwaves regress colorectal tumor tissue in mice

Cancer Treatment - Atlanta hospital opens new outpatient center with $2.5 million from AFLAC

Collaborations - Agreement signed for Oxygent development in Europe

Diagnostics - Early FAMM diagnosis and prophylaxis decreases neoplastic transformation risk

Dyskeratosis Congenita - Chromosome "caps" predict bone marrow disease

End-Stage Renal Disease - Medicare initiative aims to increase use of fistulas in providing hemodialysis

Ethics - Gene therapy studies show first successes

Finance - Diabetes-focused company reports first quarter net loss of $1.2M

Genomics - Cyclin-dependent kinase inhibitor p21 induces Flt3-ITD leukemogenesis

Genomics - Notch1 gene involved in ATRA-modulated differentiation process in APL

HIV/AIDS Hemophilia - Rare case of thrombotic thrombocytopenic purpura described

Hematology - Antisense RNA molecules select for molecules linked to sickle cell disease

Hematology - Crystal structure of E. coli dos heme domain determined

Hematology - Crystal structure of thrombin and fibrin region complex determined

Hematology - Eurya emarginata extracts inhibit leukemia cell growth via apoptosis induction

Hematology - Heparin reverses preeclampsia in a factor V Leiden mutation carrier

Hematology - Serum levels of zinc affect bone mineral density in beta-thalassemic youth

Hemochromatosis - Researchers discover a surprising link between inflammation and anemia

Hemophilia - Award given for best presentation at thrombosis and hemostasis meeting

Immunology - B lymphocytes produce normal signals despite hepatitis C virus infection

Immunology - Effects of IL-12 and -15 on neonatal NK cell activity characterized

Immunology - Genetic trick adapted from viruses makes gene-therapy vectors more versatile

Immunology - Origin and maturation of CD11b+Gr-1+ iMacs elucidated

Immunology - Potentially autoreactive NK cells present in healthy individuals

Leukemia - Arsenic trioxide in combination with ATRA yields remission, survival

Lymphoma Therapy - Allo-PBSCT with RIC feasible for children with refractory Hodgkin disease

Malaria - Platelet sequestration in malaria-induced thrombocytopenia characterized

Microbiology - Amoebae-resisting bacteria isolated from amoebal coculture

Multiple Myeloma Therapy - t translocation predicts poor auto-SCT outcome in multiple myeloma patients

Mutagenesis - Genetic factors regulate 3'-azido-3'-deoxythymidine-induced cytogenetic damage

Myelodysplastic Syndromes - Role of mtDNA mutations in MDS-leukemia transition determined

Nuclear Medicine - Tumor irradiation poses risk of bystander effect

Patents - U.S. patent filed for anti-sepsis compound

Pathogenesis - MLL gene rearrangement not pathogenic mechanism in de novo MDS

Personnel - Edward Garnett named VP of stem-cell company

Prognostics - PML tumor suppressor gene mutations indicate poor APL prognosis

Proteomics - Radical formation on hemoglobin characterized

Proteomics - System L amino acid transporter rationale for oral cancer therapy

Proteomics - Up-regulation of ubiquitin-specific protease enhances EBV proliferation in vitro

Pulmonary Hypertension - Bone marrow stem cells contribute to hypoxia-induced pulmonary vessel growth

Quality Assurance - Digital oncology documentation system integration increases quality assurance

Retrovirology - Nedd 4 or ubiquitin ligase Nedd4 regulates human T-cell leukemia virus type 1

Severe Aplastic Anemia - Purified stem cells from alternative donors feasible for pediatric SAA patients

Stem Cell Research - Adult cardiac Sca-1+ cells have stem-cell potential

Stem Cell Research - BioArchive Systems shipped to U.K., Japan, Russia, and Turkey

Stem Cell Research - Effect of Candida infection on murine hematopoiesis characterized

Stem Cell Research - Nanos prevents germline stem-cell differentiation

Stem Cell Research - Perinatal neural stem cells have bidirectional stress-dependent plasticity

Stem Cell Research - Telomerase deficiency thwarts mesenchymal stem cell differentiation

Stem Cell Transplantation - Computer system useful for drug management in bone marrow recipients

Stem Cell Transplantation - Recombinant KGF protects against GVHD in mice

Stem Cell Transplants - Cord blood banking industry flourishes amid controversy

Transfusion Medicine - Work on inorganic blood substitute to move forward with $1.5 million grant

Transplant Medicine - Doctors marvel at recovery of tiny transplant survivor

Transplant Medicine - Primary sclerosing cholangitis heightens odds for liver transplant rejection

Tuberculosis Immune Control - Novel whole blood test measures T-cell responses to TB antigens

West Nile Virus - CDC: Six people got mosquito virus through blood transfusions last year

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