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Stem Cell Research

Human neural stem cell lines are stable when cultured for long periods

Published in Blood Weekly, May 20th, 2004

Human neural stem cell lines are stable when cultured for long periods.

According to published research from Spain, "human neural stem cells (hNSCs) are excellent candidates for in vitro and in vivo molecular, cellular, and developmental research, and also for ex-vivo gene transfer and cell therapy in the nervous system. However, hNSCs are mortal somatic cells, and thus invariably enter an irreversible growth arrest after a finite number of cell divisions in culture. It has been proposed that this is due to telomere shortening.

"Here, we show that long-term cultured (up to 4 years) v-myc perpetuated hNSC lines do preserve short but stable and...

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