Published in Blood Weekly, May 27th, 2004
According to a recent report from Italy, "Endocrine turnouts of gut and pancreas tract are rare entities originating from cells of the diffuse endocrine system. The endocrine phenotype is assessed by the expression of general and specific endocrine markers.
"General endocrine markers associate to organelles like large dense core vesicles (e.g., chromogranin A) and small synaptic-like vesicles (e.g. synaptophysin), or to the cytosol, like neuron specific enolase and protein gene product 9.5 (PGP9.5). The specific markers correspond to the hormones produced by tumor...
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