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Hematology

CD7 and CD56 antigens associated with low remission rate in acute leukemia

Published in Blood Weekly, May 27th, 2004

CD7 and CD56 antigens are associated with low remission rates in acute leukemia.

"The prognostic significance of immunophenotypical properties of leukemic cells is well known. However, the biological and clinical significance of CD7 and CD56 antigen expression in acute leukemias are not clearly established.

"In patients with acute leukemias, we identified CD7 and CD56 expression and analyzed their associations with markers expressed early in hemopoietic ontogeny and clinical parameters," wrote scientists in England.

"Among 22 patients with acute leukemia [12 acute myeloblastic leukemia (AML), 10 acute lymphoblastic leukemia...

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