HIV/AIDS Research
IKK2 inhibitor alleviates kidney and wasting diseases in murine AIDS model
Published in Blood Weekly, June 3rd, 2004
"Wasting and renal diseases are frequent complications of HIV (human immunodeficiency virus) infection and are associated with accelerated disease progression and increased mortality. Transgenic mice expressing HIV-1 under control of the CD4 promoter develop an AIDS-like disease and were used in the present work to study HIV-1-induced wasting and kidney pathology," wrote scientists in Switzerland.
In the present study, "disease evolution paralleled increases in serum urea and creatinine levels, indicating an early and progressive deterioration of kidney function;...
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Source: Blood Weekly (2004-06-03)
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