Prions
Prnp transfection suppress CVB3 replication in prion protein gene-deficient cell
Published in Blood Weekly, June 3rd, 2004
"The susceptibility of prion protein gene (Prnp)-null cells to coxsackievirus B3 (CVB3) was investigated. Primary cultures of murine Prnp(-/-) brain cells were more sensitive to CVBs than corresponding cells from wild-type mice. The viral susceptibility of a Prnp-null cell line (HpL3-4) derived from the murine hippocampus was compared with that of two established cell lines (HeLa and HEp-2) that are widely employed for CVB3 studies," wrote scientists in Japan.
"After infection with CVB3, HpL3-4 cells showed a very rapid and complete cytopathic effect (CPE). CPE...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2004-06-03)
More Articles from Blood Weekly
- Blood Banking
Prestorage plasma filtration activates the complement cascade - Retrovirus
Human T-lymphotropic virus type 1 can spread directly between lymphocytes - Stem-Cell Research
Blastocyst-derived cell is source of neural derivates for differentiation study - Stem-Cell Research
Direct cell contact influences fate of bone marrow mesenchymal stem cells - Stem-Cell Research
Human neural progenitor cells possible source for treatment of Parkinson disease - Addiction Medicine
Family history predicts alcohol relapse after liver transplantation - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
