Susan Hasty, Publisher
Table of Contents . . . June 10th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cell Proliferation - Hepatocyte proliferation enhanced by immobilization on 24 nm-sized gold colloid
Stem-Cell Research - Genetic profiling of hair follicle stem cells yields treatment targets
Stem-Cell Research - Stem cells derived via nuclear transplantation regenerates infarcted heart
Stem-Cell Transplantation - IFN with very low-dose PBMC infusion induces complete remission in CML relapse
Tissue Engineering - Schwann cells implanted into acellular muscle provides graft for regeneration
Acute Coronary Syndromes - Company announces reinitiation of phase IIa trial in ACS
Acute Myeloid Leukemia - Ceplene trial in AML meets primary trial endpoint
Angiology - Platelet factor-4 and its derivatives control angiogenesis and invasion
Antimicrobials - New compounds antifungal and anticancer but inactive against HIV-1 and bacteria
Apoptosis - Cisplatin-induced apoptosis associated with mitochondrial dysregulation
Apoptosis - Cyclic AMP activation of ERK1/2 leads to transient inhibition of apoptosis
Bacteriology - Campylobacter jejuni genes involved in GI tract colonization are identified
Bioengineering - Artificial cells will pave the way for new treatment modalities
Bioengineering - Genetically modified Sertoli cells survive allogeneic transplantation
Blood - Clinical trial to investigate treatment for CIDP
Blood - Phase III efficacy results announced for plasma treatment system
Blood Safety - A new rapid molecular assay detects at least four strains of the SEN virus
Blood Safety - Transfusion-transmitted bacterial infection risks reviewed
Blood Shortage - Life-threatening blood shortages projected for New York/New Jersey
Bone Marrow - FDA approves drug for bone marrow disease
Cardiovascular Disease - Nitrates should not be given along with any of the PDE5 inhibitors
Chronic Lymphocytic Leukemia - Activation-induced cytidine deaminase (AID) may be a marker for B-CLL
Complementary and Alternative Medicine - Uncaria tomentosa extracts have potential application as immunomodulator
DNA Transcription - mTERF exists in mitochondria as active monomer and inactive large size complex
Diabetic Nephropathy - Use of cyclosporine in renal and pancreas transplantation reviewed
Diagnostics - Quantitative plasma CMV DNA assay very sensitive
Dialysis - Heparin coating of PVC tubing reduces DEHP exposure
Drug Development - MMC response cannot be predicted by NQOI or P450R protein expression
Drug Development - New factor Xa inhibitors synthesized
Endocrinology - ERalpha could play significant role in benign prostatic hyperplasia development
Endocrinology - Estrogen produces age-specific phenotypes in rat cholinergic basal forebrain
Enzymology - Proteolytic imbalance reversed after therapeutic surgery in breast cancer
Finance - BioArchive product line generates $2.2M in third quarter
Finance - Biotechnology company reports first quarter 2004 financial results
Finance - Blood-products company reports second consecutive profitable quarter
Finance - PolyHeme maker to raise $23.4 million
Gene Expression - Novel binding elements and gene targets for homeodomain protein BARX2 identified
Gene Inhibition - Silenced tazarotene-induced gene 1 negates retinoic acid responsiveness
Genomics - Cryptosporidium parvum genome completely sequenced
Genomics - Genetic alterations within DR4 gene may be implicated in osteosarcoma formation
Genomics - Low-activity serotonin transporter genotype associated with heroin dependence
HIV/AIDS Immunology - Immune and endocrine change with group intervention in early stage HIV infection
HIV/AIDS Pharmacology - Pharmacological CDK inhibitors target virus and pathogenic mechanisms
HIV/AIDS Proteomics - HIV-1 nucleocapsid protein enhances annealing approximately fivefold
HIV/AIDS Research - Aldo-keto reductase family pathway generates HP1 from S-1360
HIV/AIDS Research - Autologous p2gag peptide blocks HIV-1 virion autolysis
HIV/AIDS Research - Crystal structures of HIV protease mutants reveal indinavir-binding site changes
HIV/AIDS Research - HIV-1 APIs modulate Ca2+ signaling in secretory epithelial cells
HIV/AIDS Research - Phlorotannins from brown alga E. cava inhibit HIV-1 RT and protease
HIV/AIDS Research - Prolonged HIV-1 culture increases its sensitivity to soluble CD4 neutralization
HIV/AIDS Research - Tenofovir regimens increase K65R selection to confer multiple NRTI resistance
HIV/AIDS Virology - HIV-1 viral load and infectivity reduced in presence of cellular prion protein
HIV/HCV Treatment - HCV therapy with IFN/RBV relatively safe in patients coinfected with HIV and HCV
Heart Surgery - Polymeric sealant suitable for anastomatic bleeding control
Helicobacter Pylori - Helicobacter pylori infection high among dyspeptic patients in Ethiopia
Hepatitis B Virus - Diversity of hepatitis B virus in Dutch blood donors reported
Hepatitis B Virus - HBV DNA test should replace HBsAg and/or anti-HBc for blood donor screening
Herpesvirus - Simulect safe in pediatric renal transplant with low HHV-6 or EBV infection risk
Immunology - 5'-Methylthioadenosine modulates inflammatory response to hepatocyte endotoxin
Immunology - AOP-RANTES and heparinoids inhibit human macrophage activation
Immunology - Absence of NO production alone does not initiate endothelial cell activation
Immunology - Allicin holds promise for chronic inflammatory diseases
Immunology - Altered immune reaction linked to immunosuppressive potential of oral bactreria
Immunology - Beta-catenin signaling acts differently in prostatic or colorectal tumorigenesis
Immunology - Both macrophages and stromal cells clear apoptotic marrow-derived pre-B cells
Immunology - CyA C2 predicts total cholesterol in immunosuppressed kidney transplant patients
Immunology - Dendrites are chemoattracted to C3a after up-regulation of C3a receptor with IFN
Immunology - Distinct CXC chemokines show restricted expression in myeloid/nonmyeloid cells
Immunology - FTY720 may increase efficacy and tolerability of immunosuppressive regimens
Immunology - HIP-55 key novel component of synapse modulating T-cell activation
Immunology - Hyperfiltration not the rule following single kidney transplantation
Immunology - Medicinal fungus water extract promotes immunity and inhibits tumor metastasis
Immunology - Proinflammatory phenotype in niSMCs result in increased leukocyte recruitment
Immunology - TEPA study supports current phase I/II leukemia trial in the U.S.
Immunology - The mast cell directs the immune response
Immunology - sIg light chain restriction may not indicate mature B-cell phenotype in ALL
Immunosuppression - Cyclosporin and tacrolimus have equivalent results in lung transplantation
Immunosuppression - Cyclosporine remains the cornerstone of immunosuppression
Immunosuppression - Successful kidney transplants increase with cyclosporine experience
Infectious Disease - Transmission cycles of Pneumocystis jirovecii infections are linked
Inflammation - recHDLs reduce inflammation associated with ischemia/reperfusion and colitis
Ischemia - Stathmin marks cell proliferation in the recovery phase of renal failure
Kidney Disease - IgA nephropathy associated with X-linked thrombocytopenia
Legal Issues - Maryland hospital faces congressional review
Leukemia - MRI is an important tool in detecting recurrent acute lymphoblastic leukemia
Mergers and Acquisitions - Cell therapy company signs letter of intent to merge
Metabolic Pathway - Organelles are involved in tissue differentiation
Military Healthcare - Talent, Clinton push military health bill
Mutagenesis - Aberrant methylation of trail decoy receptor genes is common in many cancers
Neural Inflammation - Butyrate is anti-inflammatory in primary, brain-derived microglial cells
Neurology - MCP-1 involved in development of mechanical allodynia induced by nerve injury
Obstetrics - Iron supplements still leave pregnant women anemic in semirural Mexico
Opportunistic Infections - Prophylactic levofloxacin spawns drug-resistant microbes in cancer patients
Oral Surgery - Autologous fibrin-platelet glue improves maxillofacial surgery outcome
Osteoporosis - Calcium citrate decreases bone resorption markers more than calcium carbonate
Patents - Patents granted for blood volume analyzer kit in Canada, Japan
Pediatric Health - Engineer helps create world's first artificial heart for children
Pharmaceutical and Drug Development - Novel synthesis of protease inhibitors yield potent anti-HIV activity
Proteomics - Matrix gene and protein expressions change in radiation-exposed skin
SARS - Monitoring natural killer cells help differentiate SARS from M. Pneumoniae
Skin Cancer - Alpha-tocopherol may offer some protection against less aggressive melanomas
Stem Cells - New population of multilineage stem cells in umbilical cord blood isolated
Stem-Cell Research - 3-D analysis of cultured bone useful for continuous monitoring of tissue growth
Stem-Cell Research - Apoptosis requires participation of pro-apoptotic family member Bax
Stem-Cell Research - Different signaling pathways involved in pathogenesis of CML and EMS
Stem-Cell Research - Endodermal progenitors differentiate into hepatic and pancreatic lineages
Stem-Cell Research - Enhanced stem cell survival associated with specific APC mutations
Stem-Cell Research - Greater understanding of ocular stem-cell biology needed
Stem-Cell Research - Improved embryonic stem cell test predicts developmental toxicity
Stem-Cell Research - LIMK1/cofilin-mediated actin reorganization regulates stem cell migration
Stem-Cell Research - Many brainstem neurons express functional MOR or DOR receptors or both
Stem-Cell Research - Novel biomarkers of human pluripotent embryonic carcinoma stem cells identified
Stem-Cell Research - Novel method useful for cell-cell interaction studies and tissue engineering
Stem-Cell Research - Novel neuronal phenotypes generated from neural progenitor cells
Stem-Cell Research - Shock wave-promoted bone formation activates ERK and p38 kinase
Stem-Cell Research - Skin-originated stem cells isolated from pigs
Stem-Cell Research - Soluble Jagged-1 induces hematopoietic stem cell self-renewal
Stem-Cell Research - c-Kit and nestin expressing cells represent endocrine precursor cells
Stem-Cell Transplantation - Allogeneic stem cell transplant curative in amegakaryocytic thrombocytopenia
Stem-Cell Transplantation - Cell transplantation for Parkinson disease still in infancy
Stem-Cell Transplantation - Children recovering from stem-cell transplants suffer diminished resistance
Stem-Cell Transplantation - Pretreatment with hydroxyurea lowers rejection incidence in sickle cell disease
Thromboembolic Disorders - Anticoagulant for thromboembolic disorders effective in animal models
Tissue Engineering - Biodegradable support materials used to produce biphasic cartilage constructs
Tissue Engineering - Inkjet printing used for high-throughput cell patterning
Tissue Engineering - Preincubating tissue engineered constructs enhances donor cell retention
Transfusion Medicine - FACS assay suitable for HPA 1a screening
Transgenics - Pentraxin 3 helps control fungal recognition and phagocytosis
Transplant Medicine - Report: New approach has lung recipients taking far fewer drugs
Tumor Marker - Clinical marker CAF-1 distinguishes quiescent from proliferating cells
Tumor Suppression - PTEN is physically associated with platelet-derived growth factor
Tumorigenesis - Autocrine/paracrine SFRP 2 induces cellular resistance to apoptosis
West Nile - North Carolina health officials warn of West Nile threat
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