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Tissue Engineering

Biodegradable support materials used to produce biphasic cartilage constructs

Published in Blood Weekly, June 10th, 2004

Biodegradable support materials have been used to produce biphasic cartilage constructs.

"Biological restoration of osteochondral defects requires suitable subchondral support material that also allows the induction of hyaline cartilage tissue. Biphasic implants consisting of pre-fabricated neocartilage and an underlying biodegradable osteoconductive base may meet these requirements. Here we explore various candidate biodegradable support materials onto which neo-cartilage was produced in vitro," researchers in Switzerland report.

"Porcine chondrocytes were seeded in a closed and static bioreactor with a base of biomaterial consisting of either...

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