Endocrinology
ERalpha could play significant role in benign prostatic hyperplasia development
Published in Blood Weekly, June 10th, 2004
According to recent research published in the journal Prostate Cancer and Prostatic Diseases, "This study investigated the hypothesis that, in benign prostatic hyperplasia (BPH), upregulated estrogen receptors (ER) and the action of androgens differentially regulate expression of stromal growth factors.
"Eight human prostatic stromal cell strains were subjected to a procedure to upregulate their ER by exposing them to 1 mcM 17beta-estradiol for 10 days followed by passage and growth in the absence of steroids. Four of the cell strains instead received 100...
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Source: Blood Weekly (2004-06-10)
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