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Tissue Engineering

Schwann cells implanted into acellular muscle provides graft for regeneration

Published in Blood Weekly, June 10th, 2004

Schwann cells implanted into an acellular muscle provides a graft for regeneration.

"Tissue-engineering as laboratory based alternative to human autografts and allografts provides 'custom made organs' cultured from patient's material. To overcome the limited donor nerve availability different biologic nerve grafts were engineered in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into acellular autologous matrices: veins, muscles, nerves, and epineurium tubes. Autologous nerve grafts, and the respective biogenic material without Schwann cells served as control," researchers in Germany report.

"After 6 weeks regeneration was...

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