Immunology
Absence of NO production alone does not initiate endothelial cell activation
Published in Blood Weekly, June 10th, 2004
According to a study from Massachusetts General Hospital-East, "The objective of this study was to determine whether absence of endothelial nitric oxide synthase (eNOS) affects the expression of cell surface adhesion molecules in endothelial cells."
"Murine lung endothelial cells (MLECs) were prepared by immunomagnetic bead selection from wild-type and eNOS knockout mice. Wild-type cells expressed eNOS, but eNOS knockout cells did not," reported P.J. Kuhlencordt and coworkers.
"Expression of neuronal NOS and inducible NOS was not detectable in cells of...
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Source: Blood Weekly (2004-06-10)
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