Susan Hasty, Publisher
Table of Contents . . . June 24th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Cardiovascular Disease - Metabolic syndrome positively associated with cardiovascular disease
Skin Cancer - More UVA than UVB fingerprint mutations in basal layer of human squamous tumors
Stem-Cell Research - Dopaminergic neurons generated from embryonic stem cells
Stem-Cell Research - Embryonic stem cells are an alternate marrow donor source
Tissue Engineering - Cartilage tissue regenerated by serum-free cultured chrondrocyte implantation
Allergy & Immunology - PAR-2-mediated activation enhances airway inflammation
Allergy Medicine - PAF responsiveness in subjects with plasma PAF acetylhydrolase deficiency
Allergy Medicine - Test methods evolving for newly emerging allergy epidemics
Anemia - Successful cord blood stem cell transplant reported
Antibacterial Research - NMR evidence found for independent domain structures in zoocin A
Antiphospholipid Syndrome - Endothelial microparticles may play role in thrombotic complications of APS
Apoptosis - Labeled Annexin A5 detects programmed cell death in vitro and in vivo
Assisted Reproduction - Medically assisted reproduction still risky in presence of chronic viral disease
Atherosclerosis - PAD patients should be aggressively treated for atherosclerotic risk factors
Bacteriology - Histopathologic changes in kidney and liver correlate with SPE B production
Biotechnology - Cytokine flow cytometry assesses cellular immune responses to viral antigens
Bleeding - Application submitted to FDA to market autologous thrombin processing device
Blood Banking - Autologous FG by CryoSeal FS System suggestive for hypothetical blood saving
Blood Screening - Consensus determines principles of screening and prevention of vCJD
Breast Cancer Survival and Mortality - CD105 identifies node-negative breast cancer patients with poor prognoses
Cancer Cell Biology - Perpetual cancer from leukemic stem cells described
Cancer Diagnosis - Immunomagnetic separation depicts esophageal cancer micrometastasis
Cancer Research - CEACAM6 crosslinking leads to increased extracellular matrix component adhesion
Cancer Therapy - Amifostine does not protect lungs from carmustine-containing chemotherapy
Cancer Treatment - Utah doctors determine 'good, bad' chemo
Cardiology - Cigarette smoking predicts reduced maximal FEV1 level in males but not females
Cardiology - Potential treatment for aortic aneurysm repair surgery given FDA fast track status
Cholesterol - Cholesterol regulates GCase activity/stability in Niemann-Pick disease type C
Chronic Lymphocytic Leukemia - Rituximab called most promising emerging drug for chronic lymphocytic leukemia
Chronic Myeloid Leukemia - A few questions remain concerning chronic myeloid leukemia
Collaborations - Option granted for rights to blood platelet modification technology
Complementary & Alternative Medicine - Licorice extract significantly improves learning and memory
Coronavirus - Previously undescribed coronavirus associated with respiratory disease in humans
Crosslinking - RPA binds primer-template junction in absence of its major ssDNA-binding domains
Cytomegalovirus - Inverse correlation between CD27 quantitation and cytotoxic effector function
Detection - RAPD analysis useful for genotyping clinical Candida spp. isolates
Diagnostics - Automated schistocyte counting method evaluated
Diagnostics - Flow cytometry is utilized to study natural killer T cells
Drug Advertising - FDA warning letter issued on promotional materials for Advate
Drug Development - Chitosan microspheres potential carrier for drugs
Drug Resistance - Topoisomerase II alpha foils the effectiveness of etoposide in myeloma cells
Finance - $3M private placement to fund Oxycyte blood substitute clinical trials
Gastroenterology - Promising therapies available for the treatment of Crohn disease
Gene Transfer - 2-Amine is major bystander metabolite when CB 1954 is activated by NTR in tumors
Genetic Engineering - Stem cell factor gene-modified natural killer cells overwhelm tumor cells
Genomics - Gene encoding C. stercorarium beta-xylosidase Xyl43B in E. coli sequenced
Genomics - p16(INK4a) and p53 tumor suppressor genes altered in hTERT-immortalized cells
Gynecology - Polycystic ovary follicular excess may be main culprit for follicular arrest
HIV Diagnosis - HIV-1/2 oral fluid rapid tests under development
HIV/AIDS - AIDS-related NHL is treated traditionally as supportive care improves
HIV/AIDS - Argininamide binding arrests global motions in HIV-1 TAR RNA
HIV/AIDS - Ezrin/CD95 linkage key role regulating susceptibility to CD95-mediated apoptosis
HIV/AIDS - Intracellularly expressed HIV-1 Tat protein inhibits neural cell proliferation
HIV/AIDS Gene Therapy - TAT-pK/DNA complex useful way to package therapeutic genes for cell transduction
HIV/AIDS Progression - Timed ablation of regulatory CD4+ T cells prevents AIDS progression
HIV/AIDS Research - Central domain of HIV-1 matrix protein influences virus infectivity
HIV/AIDS Research - Channels formed by Vpu result from the self-assembly of monomers
HIV/AIDS Research - FIV env-mediated fusion mechanism and kinetics are similar to HIV env
HIV/AIDS Research - Overexpression of Oct-1 or -2 has no effect on HIV-1 transcription in CD4 cells
HIV/AIDS Treatment - Cell surface targets identified for HIV-1 therapeutics using genetic screens
Health Risk - Boy dies of blood infection; friends, relatives treated
Health and Fitness - Multiple myeloma patients commit to exercise based on a number of factors
Heart Failure - Anemia adversely affects outcome of diastolic heart failure patients
Hematology - Age and packed cell transfusion volume act synergistically to increase mortality
Hematology - Bfl-1/A1 is a potent antiapoptotic stimulant in myeloma cells
Hematology - Cryoprecipitate-removed plasma is factor IX source for treatment of hemophilia B
Hematology - Updated results presented from phase III study of Dacogen in MDS
Hemophilia A - Linkage analysis and antigen assay detects 50% of carriers
Hepatitis C - Oral prodrug selected for front-line treatment of chronic hepatitis C
Hepatitis C Virus - Combinations of Ig GM and KM phenotypes associated with outcome of HCV infection
Herpesvirus - HHV-8 vFLIP essential for survival of infected lymphoma cells
Immunology - Angiotensin II receptors modulate murine macrophage activity and phagocytosis
Immunology - Anti-Gal IgG potentiates NK cell migration via endothelial cell activation
Immunology - Neuropeptides do not induce mediator release in isolated intestinal mast cells
Immunology - Novel polymorphism in cytoplasmic region of IgA Fc receptor gene found
Immunology - Protection against infection may depend upon healthy host-microbe interactions
Immunology - Reduced B cell CD22 expression does not effect S. aureus arthritis and sepsis
Immunology - S1P receptor activation by FcepsilonRI trigger required for mast cell function
Immunology - Selected peptides functionally represent the Fc-gammaRII-binding part of IgG1
Infectious Disease - Modes of hantavirus transmission inferred from mitochondrial DNA analyses
Leukemia - Elderly patients benefit from intensive treatment
Leukemia - U.S. research hospital helps Brazilian children fight leukemia
Liver Disease - Nonalcoholic fatty liver disease encompass benign steatosis and steatohepatitis
Liver Failure - Treatment options vary for acute liver failure
Lymphoma - Initial bone marrow involvement is infrequent in nasal-type NK/T cell lymphoma
Measles Outbreaks - Measles outbreak control in adult populations discussed
Molecular Diagnostics - Molecular typing techniques are useful for detecting pathogenic fungi
Myelodysplastic Syndromes - FDA approves Vidaza (azacitidine for injectable suspension) for MDS
Neuroblastoma - Salvage therapy influences survival in children with recurrent neuroblastoma
Neuroscience - Alterations in tau transcripts correlate with sporadic tauopathy neurofilament
Neuroscience - proNGF exhibits neurotrophic activity but is less active than mature NGF
Non-Hodgkin Lymphoma - Extranodal non-Hodgkin lymphoma can occur in the sinonasal tract
Non-Hodgkin Lymphoma - Pesticide exposure is not related to increased risk of NHL in southern Sweden
Obstetrics - Factor V Leiden associated with increased risk of obstetric complications
Oncogenesis - Many genes synergize with Cbfb-MYH11 to produce acute myeloid leukemia
Oncology - Thalidomide treats multiple myeloma by targeting bone marrow angiogenesis
Phenotyping - EBV-transformed B-cell lines used for reference and research in routine lab
Protozoal Infection - CTLA-4 blockage increases resistance to infection with Trypanosoma cruzi
Recurrent Spontaneous Abortion - Elevated maternal plasma levels of factor VIII linked to increased RSA risk
Retrovirus - FIV replication in activated CD4+CD25+T cells independent of cell proliferation
Stem Cells - Preclinical studies show that stem cells may reverse diabetes in mice
Stem-Cell Research - Activated neural stem cells contribute to stroke-induced neurogenesis
Stem-Cell Research - Allogeneic PBSCT is feasible for children with beta/beta and beta/E
Stem-Cell Research - BMP-2 controls key early commitment step in embryonic stem cell differentiation
Stem-Cell Research - Cord blood stem cells plus fibrin platelet glue used for wound repair
Stem-Cell Research - Developing neonatal rabbit appendix is seeded by immature blood-borne B cells
Stem-Cell Research - GAMT deficiency causes biochemical adaptations in brain and skeletal muscle
Stem-Cell Research - Large defect bone reconstruction using BM-derived SSC not proven for non-union
Stem-Cell Research - Mesenchymal stem cells from adult mouse bone marrow isolated and characterized
Stem-Cell Research - Novel DZIP gene expressed in embryonic stem cells and germ cells is identified
Stem-Cell Research - Nucleosome remodeling defect prevents IL-12(P35) transcription in neonatal DC
Stem-Cell Research - Pluripotent stem cell line expressing the AML1-ETO fusion protein established
Stem-Cell Research - Poly(NiPA-co-AAc) gel may provide optimal chondrocyte propagation 3D environment
Stem-Cell Research - Regenerative response in ischemic brain is restricted by p21(Cip1/waf1)
Stem-Cell Research - Side population cells in human/mouse epidermis lack stem cell characteristics
Stem-Cell Research - Skeletal muscle differentiation potential of adult BM cells may lead to therapy
Stem-Cell Transplantation - Allogeneic hematopoietic stem cell transplant for lymphoma should be selective
Stem-Cell Transplantation - Predictors of outcome identified in patients with metastatic rhabdomyosarcoma
Tissue Engineering - Endocytosis of nano-environment produced by colloidal lithography by fibroblasts
Tissue Engineering - Nanocolumns produced for cell culture using colloidal lithography
Tissue Engineering - Web-like structured novel sheet promising for custom-shaped bone regeneration
Transfusion Medicine - GB virus C/hepatitis G virus infections are rare and self-limiting in India
Ultrasonography - Ultrasound affects structure and function of proteins of PPSB complex
Viral Disease - Biotech company testing possible antidote for bioterrorism viruses
Virology - Dendritic cell-associated function impairment distinguish HCV and HIV infection
Virology - Human Coronavirus 229E in nasal specimens detected by RT-PCR hybridization assay
West Nile Virus - West Nile virus-associated encephalitis seen in immunocompromised patients
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