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Stem-Cell Research

Activated neural stem cells contribute to stroke-induced neurogenesis

Published in Blood Weekly, June 24th, 2004

Activated neural stem cells contribute to stroke-induced neurogenesis.

According to recent research from the United States, "Stroke increases neurogenesis. The authors investigated whether neural stem cells or progenitor cells in the adult subventricular zone (SVZ) of rats contribute to stroke-induced increase in neurogenesis."

"After induction of stroke in rats, the numbers of cells immunoreactive to doublecortin, a marker for immature neurons, increased in the ipsilateral SVZ and striatum. Infusion of an antimitotic agent (cytosine-beta-D-arabiofuranoside, Ara-C) onto the ipsilateral cortex eliminated more than 98% of actively proliferating cells...

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