Renal Failure
AGE-modified materials may underlie prurigo in dialysis patients
Published in Blood Weekly, July 1st, 2004
Physicians in Japan described their experience with "two patients with chronic prurigo who suffered from chronic renal failure and were treated by hemodialysis."
"Histological examination of pruritic nodules revealed that the papillary dermis of the lesional skin was eosinophilic and amorphous, and free from dermal cell infiltration," noted N. Fujimoto and coauthors at the National Defense Medical College in Saitama.
"Immunohistochemical study demonstrated that advanced glycation end product (AGE)-immunoreactive materials accumulated in the papillary...
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Source: Blood Weekly (2004-07-01)
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