HIV/AIDS Genetics
Random genetic drift influences HIV-I env evolution during chronic infection
Published in Blood Weekly, July 1st, 2004
According to published research from the United States, "Human immunodeficiency virus type I (HIV-1) has high replication and mutation rates that generate large census populations and high levels of genetic variation. We examined the roles of natural selection, population growth, random genetic drift, and recombination in shaping the variation in 1509 C2-V5 env sequences derived from nine men with chronic HIV-1 infection."
"These sequences were obtained from clinical visits that reflect the first 6-13.7 years of infection. Pairwise comparisons of nonsynonymous and...
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Source: Blood Weekly (2004-07-01)
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