Neuroscience
Cortical and subcortical GABA function may be compromised in schizophrenia
Published in Blood Weekly, July 22nd, 2004
According to published research from the United States, "Gamma-Aminobutyric acid (GABA), the principal inhibitory neurotransmitter of CNS, has been consistently implicated in the pathophysiology of schizophrenia. GABA is synthesized from glutamate by the enzyme glutamic acid decarboxylase (GAD). Two isoforms of GAD have been identified and have been named GAD65 and GAD67 based on their apparent molecular weights."
"In this study," S. Dracheva and colleagues wrote, "GAD65 and GAD67 rnRNA and protein levels were measured by using real-time RT-PCR and immunoblotting,...
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Source: Blood Weekly (2004-07-22)
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