Preimplantation Genetic Diagnosis
Real-time PCR clinically useful for single-cell genotyping in blood diseases
Published in Blood Weekly, July 29th, 2004
"Sickle-cell and beta-thalassemia syndromes are priority genetic diseases for prevention programs involving population screening with the option of prenatal diagnosis for carrier couples. Preimplantation genetic diagnosis (PGD) represents a specialized alternative to prenatal diagnosis and is most appropriately used for couples with an unsuccessful reproductive history and/or undergoing assisted reproduction. However, clinical application of PGD has been hindered by...
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Source: Blood Weekly (2004-07-29)
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