Viral Pneumonia
Increased SP-A/defensin mRNA coincides with reduced viral load in pneumonia
Published in Blood Weekly, July 29th, 2004
"Defensins and surfactant protein A (SP-A) and SP-D are antimicrobial components of the pulmonary innate immune system. The purpose of this study was to determine the extent to which parainfluenza type 3 virus infection in neonatal lambs alters expression of sheep beta-defensin 1 (SBD-1), SP-A, and SP-D, all of which are constitutively transcribed by respiratory epithelia," wrote scientists in the journal Clinical and Diagnostic Laboratory Immunology.
"Parainfluenza type 3 viral antigen was detected by immunohistochemistry (IHC) in...
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Source: Blood Weekly (2004-07-29)
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