Bacteriology
Novel secreted enzyme from E. faecalis may cause pathogenesis and persistance
Published in Blood Weekly, July 29th, 2004
According to a study from the United States, "The human pathogen Enterococcus faecalis can degrade the N-linked glycans of human RNase B to acquire nutrients, but no gene or protein has been associated with this activity."
"We identified an 88-kDa secreted protein, endoglycosidase (Endo) E, which is most likely responsible for this activity. EndoE, encoded by ndoE, consists of an alpha-domain with a family 18 glycosyl hydrolase motif and a beta-domain similar to family 20 glycosyl hydrolases.
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Source: Blood Weekly (2004-07-29)
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