Bacteriology
TIMP-1 protects against Pseudomonas aeruginosa-induced corneal destruction
Published in Blood Weekly, July 29th, 2004
According to a study from the United States, "To establish the role of TIMP-1 in protection against Pseudontonas aeruginosa-induced corneal destruction, corneas of adult 8-week-old (resistant) and aged 12-month-old (susceptible) mice were infected with the bacterium."
"Corneas were analyzed for TIMP-1 protein by immunocytochemistry and Western blotting. Basement membrane (BM) integrity was assessed by immunostaining for type IV collagen.
"Additionally," K.A. Kernackin and colleagues wrote, "resistant 8-week-old mice were treated systemically...
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Source: Blood Weekly (2004-07-29)
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