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Myeloma

Thalidomide's promising future in fighting cancer explored

Published in Blood Weekly, August 5th, 2004

From the late 1950s to the end of 1961, thalidomide was a popular sedative and treatment for morning sickness until it was discovered to cause fetal malformations, which proved fatal within the first year of life in 40% of affected infants.

The drug was never marketed in the United States or approved by the U.S. Food and Drug Administration. But researchers recognized the drug's properties might have cancer-fighting potential. This possibility has driven promising studies into thalidomide's role in fighting blood disorders, such as multiple myeloma, a deadly cancer for which there is no cure.

Mayo Clinic Proceedings has published four studies...

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